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SAR407899 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752521

SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAR407899, Inhibitor
Full Product Name
SAR407899
Product Gene Name
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
244.29
Formula
C14H16N2O2
CAS
923359-38-0
Smiles
O=c1[nH]ccc2cc(OC3CCNCC3)ccc12
Receptor (IC50)
Rho
Solubility
DMSO: 6mg/mL (24.56mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for SAR407899, inhibitor

Structure of SAR407899, inhibitor

SAR407899 Inhibitor – Cat# MBS5752521

Product References and Citations for SAR407899, inhibitor

1. Guagnini F, Ferazzini M, Grasso M, et al. Erectile properties of the Rho-kinase inhibitor SAR407899 in diabetic animals and human isolated corpora cavernosa[J]. Journal of Translational Medicine, 2012, 10 (1):59-0.
2. Grisk O, Schlüter T, Reimer N, et al.The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries[J].J Hypertens. 2012 May;30 (5):980-9.

Other Notes

Small volumes of SAR407899, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAR407899 purchase

MBS5752521 is an inhibitor targeting SAR407899.
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