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SB236057 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5778362

SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a potent teratogen, producing severe… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB236057, Inhibitor
Full Product Name
SB236057
Product Gene Name
SB236057, inhibitor
Product Synonym Names
SB 236057; SB-236057
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
534.66
SMILES
CCN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5nnc(C)o5)c4cc23)CC1
Formula
C33H34N4O3
CAS Number
180083-49-2
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)

Structure of SB236057, inhibitor

SB236057, CAS 180083-49-2
SB236057 Inhibitor – Cat# MBS5778362

Structure of SB236057, inhibitor

SB236057, CAS 180083-49-2
SB236057 Inhibitor, Structure – Cat# MBS5778362

Product References and Citations for SB236057, inhibitor

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1 Middlemis DN Göther M Schlicke E Scot CM Selkir JV Watso J Gaste LM Wyma P Rile G Pric GW SB-236057 selectiv 5-HT1 recepto invers agonist block th 5-H PUMA termina autoreceptor Europea Journa o Pharmacology 1999 75(1-3):359-65 PMI 1044358 href="javascript:void(0) rel="nofollow >
2 Robert C Watso J Pric GW Middlemis DN SB-236057-A selectiv 5-HT1 recepto invers agonist CN Dru Reviews 2001 (4):433-44 PMI 11830759

Other Notes

Small volumes of SB236057, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB236057 purchase

MBS5778362 is an inhibitor targeting SB236057.
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