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SMI-4a Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS386186

SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. Mostly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases. More details

$175 / 10 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMI-4a, Inhibitor
Full Product Name
SMI-4a
Product Synonym Names
SMI4a
Form/Format
Powder
Purity/Purification
>98%
Concentration
0.1 mM: 36.6 mL (1 mg); 183.02 mL (5 mg); 366.03mL (10 mg)
0.5 mM: 7.32 mL (1 mg); 36.6 mL (5 mg); 73.21 mL (10 mg)
1 mM: 3.66 mL (1 mg); 18.3 mL (5 mg); 36.6 mL (10 mg)
5 mM: 0.73 mL (1 mg); 3.66 mL (5 mg); 7.32 mL (10 mg) (lot specific)
Preparation and Storage
at -20 degree C 3 years Powder
Molecular Weight
273.2
CAS Number
327033-36-3
Formula
C11H6F3NO2S
SMILES
O=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2
Actions
Inhibitor
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.

Chemical Structure of SMI-4a, inhibitor

SMI-4a Inhibitor – Cat# MBS386186

Product References and Citations for SMI-4a, inhibitor

Liong S, .et al. Placental Pim-1 expression is increased in obesity and regulates cytokine- and toll-like receptor-mediated inflammation, Placenta, 2017, May;53:101-112 PMID: 28487013

Other Notes

Small volumes of SMI-4a, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMI-4a purchase

MBS386186 is an inhibitor targeting SMI-4a.
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