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sodium Camptothecin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5785657

sodium Camptothecin is a plant alkaloid with Antitumor activity. sodium Camptothecin is a reversible RNA synthesis inhibitor. sodium Camptothecin is an effective adenovirus replication inhibitor. sodium Camptothecin inhibits DNA synthesis and causes breaks in… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
sodium Camptothecin, Inhibitor
Full Product Name
sodium Camptothecin
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
388.355
SMILES
[Na+].CCC(O)(C([O-])=O)c1cc2-c3nc4ccccc4cc3Cn2c(=O)c1CO
Formula
C20H17N2NaO5
CAS Number
25387-67-1
Target
DNA/RNA Synthesis
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
sodium Camptothecin (5uM; 10 min) causes a severe inhibition of heterogeneously sedimenting nuclear RNA (HnRNA) synthesis [1]. sodium Camptothecin also blocks a specific step in the processing of ribosomal precursor RNA, allowing the conversion of 45S RNA to 32S RNA while inhibiting the conversion of 32S RNA to 28S RNA [1].

Product Categories/Family for sodium Camptothecin, inhibitor

Cell Cycle/Checkpoint; DNA Damage/DNA Repair

Structure of sodium Camptothecin, inhibitor

sodium Camptothecin, CAS 25387-67-1
sodium Camptothecin Inhibitor – Cat# MBS5785657

Structure of sodium Camptothecin, inhibitor

sodium Camptothecin, CAS 25387-67-1
sodium Camptothecin Inhibitor, Structure – Cat# MBS5785657

Product References and Citations for sodium Camptothecin, inhibitor

1 Wu e al Ribosom formatio i blocke b camptothecin reversibl inhibito o RN synthesis Pro Nat Aca Sc A 197 Dec 8(12):3009-14.
2 Horwitz e al Camptothecin mechanis o inhibitio o adenoviru formation Virology 197 Jun 8(3):690-8

Other Notes

Small volumes of sodium Camptothecin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for sodium Camptothecin purchase

MBS5785657 is an inhibitor targeting sodium Camptothecin.
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