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SRC Inhibitor – Inhibitor 3

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5767648

MBS5767648 is an inhibitor targeting Src. Also known as Src Inhibitor 3. Src Inhibitor 3 is an effective inhibitor of c-terminal Src kinase (IC50 More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Src Inhibitor 3, Inhibitor
Full Product Name
Src Inhibitor 3
Product Gene Name
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
671.13
SMILES
COc1ccc2c(cnn2c1)C(=O)Nc1ccc(NC(=O)c2nn(C3CCN(CC3)C(=O)CC(C)(C)C#N)c3ccc(F)cc23)cc1Cl
Formula
C34H32ClFN8O4
CAS Number
2380027-49-4
Target
Others|||Src
c-terminal Src kinase in Caliper assay: 4nM, c-terminal Src kinase in CSK HTRF assay: <3nM
Solubility
DMSO: 95mg/mL (141.55 mM),
Need ultrasonic
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
Src Inhibitor 3 (oral) reduces inhibitory LCK phosphorylation in vivo and shows the ability to enhance T cell activation in response to antigen stimulation[1].

Structure of Src, inhibitor

Src Inhibitor 3, CAS 2380027-49-4
SRC Inhibitor – Cat# MBS5767648

Structure of Src, inhibitor

Src Inhibitor 3, CAS 2380027-49-4
SRC Inhibitor, Structure – Cat# MBS5767648

Product References and Citations for Src, inhibitor

1 O'Malle DP e al Discover o Pyridazinon an Pyrazolo[1,5-]pyridin Inhibitor o C-Termina Sr Kinase AC Me Che Lett 201 Se 25 0(10):1486-1491.

Other Notes

Small volumes of Src, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Src. It may not necessarily be applicable to this product.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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