TASP0415914 Inhibitor

Name: TASP0415914 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758741
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758741

TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase gamma (PI3Kgamma). T More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TASP0415914, Inhibitor

Full Product Name

TASP0415914

Product Gene Name

TASP0415914, inhibitor

Form/Format

Solid. Powder

Purity/Purification

100.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

323.37

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C13H17N5O3S

SMILES

CC(=O)Nc1nc(C)c(-c2nc(N3CCCC(O)C3)no2)s1

CAS Number

1292300-75-4

Target & IC50

PI3Kgamma

In Vitro

TASP0415914 demonstrated good potency in a cell-based assay and, furthermore, exhibited in vivo efficacy in a collagen induced arthritis (CIA) model in mice after oral administration[1].

Product Categories/Family for TASP0415914, inhibitor

PI3K/Akt/mTOR signaling; PI3K

Product References and Citations for TASP0415914, inhibitor

Oka Y, Yabuuchi T, Oi T, et al. Discovery of N-{5-[3-(3-hydroxypiperidin-1-yl)-1,2,4-oxadiazol-5-yl]-4-methyl-1,3-thiazol-2-ylacetamide (TASP0415914) as an orally potent phosphoinositide 3-kinase gamma inhibitor for the treatment,of inflammatory diseases[J]. Bioorganic & Medicinal Chemistry, 2013, 21(24):7578-7583.

Other Notes

Small volumes of TASP0415914, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TASP0415914 purchase

MBS5758741 is an inhibitor targeting TASP0415914.