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TCO Inhibitor – Amine

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5770039

TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TCO-amine, Inhibitor
Full Product Name
TCO-amine
Product Gene Name
TCO, inhibitor
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
226.32
SMILES
NCCCNC(=O)OC1CCC\C=C/CC1
Formula
C12H22N2O2
CAS Number
1609736-43-7
Target
Others
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Product Categories/Family for TCO, inhibitor

Others

Structure of TCO, inhibitor

TCO-amine, CAS 1609736-43-7
TCO Inhibitor – Cat# MBS5770039

Structure of TCO, inhibitor

TCO-amine, CAS 1609736-43-7
TCO Inhibitor, Structure – Cat# MBS5770039

Product References and Citations for TCO, inhibitor

1 A S e al Small-molecul PROTACs A emergin an promisin approac fo th developmen o targete therap drugs EBioMedicine 201 Oct 6:553-562

Other Notes

Small volumes of TCO, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TCO purchase

MBS5770039 is an inhibitor targeting TCO. Also known as TCO-amine.
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