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TGX-221 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS386291

TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β. More details

$155 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TGX-221, Inhibitor
Full Product Name
TGX-221
Product Synonym Names
TGX221
Form/Format
Powder
Purity/Purification
>98%
Concentration
0.1 mM: 27.44 mL (1 mg); 137.21 mL (5 mg); 274.42mL (10 mg)
0.5 mM: 5.49 mL (1 mg); 27.44 mL (5 mg); 54.88 mL (10 mg)
1 mM: 2.74 mL (1 mg); 13.72 mL (5 mg); 27.44 mL (10 mg)
5 mM: 0.55 mL (1 mg); 2.74 mL (5 mg); 5.49 mL (10 mg) (lot specific)
Preparation and Storage
at -20 degree C 3 years Powder
Molecular Weight
364.4
CAS Number
663619-89-4
Formula
C21H24N4O2
SMILES
CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4
Actions
Inhibitor
In Vivo Solvent
1% DMSO/30% polyethylene glycol/1% Tween 80
Solubility (DMSO)
12 mg/mL (32.92 mM)
Solubility (Ethanol)
<1 mg/mL (<1 mM)
Solubility (in vivo)
30 mg/mL
Solubility (Water)
<1 mg/mL (<1 mM)
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.

Chemical Structure of TGX-221, inhibitor

TGX-221 Inhibitor – Cat# MBS386291

Product References and Citations for TGX-221, inhibitor

Pridham KJ, .et al. PIK3CB/p110β is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

Other Notes

Small volumes of TGX-221, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGX-221 purchase

MBS386291 is an inhibitor targeting TGX-221.
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