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Thalidomide-O-PEG4-azide Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5771686

Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Thalidomide-O-PEG4-azide, Inhibitor
Full Product Name
Thalidomide-O-PEG4-azide
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
519.511
SMILES
[N-]=[N+]=NCCOCCOCCOCCOCCOc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Formula
C23H29N5O9
CAS Number
2380318-57-8
Target
Others
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Product Categories/Family for Thalidomide-O-PEG4-azide, inhibitor

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Structure of Thalidomide-O-PEG4-azide, inhibitor

Thalidomide-O-PEG4-azide, CAS 2380318-57-8
Thalidomide-O-PEG4-azide Inhibitor – Cat# MBS5771686

Structure of Thalidomide-O-PEG4-azide, inhibitor

Thalidomide-O-PEG4-azide, CAS 2380318-57-8
Thalidomide-O-PEG4-azide Inhibitor, Structure – Cat# MBS5771686

Product References and Citations for Thalidomide-O-PEG4-azide, inhibitor

1 A S e al Small-molecul PROTACs A emergin an promisin approac fo th developmen o targete therap drugs EBioMedicine 201 Oct 6:553-562

Other Notes

Small volumes of Thalidomide-O-PEG4-azide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5771686 is an inhibitor targeting Thalidomide-O-PEG4-azide.
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