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TPCK Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759155

TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TPCK, Inhibitor
Full Product Name
TPCK
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
96.77%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
351.84
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C17H18ClNO3S
SMILES
Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)CCl
CAS Number
402-71-1
Target & IC50
chymotrypsin-like proteases

Structure of TPCK, inhibitor

TPCK Inhibitor – Cat# MBS5759155

Product References and Citations for TPCK, inhibitor

Rana Anjum, Eunice Pae,et al. TPCK Inhibits AGC Kinases by Direct Activation Loop Adduction at Phenylalanine-Directed Cysteine Residues. FEBS Lett. 2012 Sep 21;586(19):3471-6.
Rana Anjum, Eunice Pae,et al. TPCK Inhibits AGC Kinases by Direct Activation Loop Adduction at Phenylalanine-Directed Cysteine Residues. FEBS Lett. 2012 Sep 21;586(19):3471-6.
Cocco E, et al. KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumoraggressiveness and target of KAT inhibitor CPTH Clin Epigenetics. 2018 Apr 4;10:44.
Cocco E, et al. KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumoraggressiveness and target of KAT inhibitor CPTH2. Clin Epigenetics. 2018 Apr 4;10:44.

Other Notes

Small volumes of TPCK, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TPCK purchase

MBS5759155 is an inhibitor targeting TPCK.

Additional Details

NCBI/Uniprot data below describe general gene information for TPCK. It may not necessarily be applicable to this product.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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