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ULK-101 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751814

ULK-101 is a potent and selective ULK1 inhibitor (IC50s: 8.3/30nM for ULK1/ULK2). It can suppress autophagy. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ULK-101, Inhibitor
Full Product Name
ULK-101
Product Gene Name
Form/Format
Powder
Purity/Purification
98.05%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
460.45
Formula
C22H16F4N4OS
Smiles
Fc1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)N[C@@H](C1CC1)C(F)(F)F
Receptor (IC50)
ULK1, ULK2
Solubility
DMSO: 80mg/mL (173.74mM)
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for ULK-101, inhibitor

Structure of ULK-101, inhibitor

ULK-101 Inhibitor – Cat# MBS5751814

Product References and Citations for ULK-101, inhibitor

1. Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.

Other Notes

Small volumes of ULK-101, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ULK-101 purchase

MBS5751814 is an inhibitor targeting ULK-101.
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