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VPC-70063 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5785987

VPC-70063 is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9uM and Myc-Max/UBE2C downstream pathway inhibition of 94%. VPC-70063 can be used for studies about anticancer. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VPC-70063, Inhibitor
Full Product Name
VPC-70063
Product Gene Name
VPC-70063, inhibitor
Product Synonym Names
Thiourea; N-[3;5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-
Purity/Purification
99.93%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
378.33
SMILES
FC(F)(F)C1=CC(=CC(=C1)C(F)(F)F)NC(=S)NCC=2C=CC=CC2
Formula
C16H12F6N2S
CAS Number
13571-44-3
Target
Apoptosis|||PARP|||c-Myc
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
VPC-70063 (6.25, 12.5, and 25uM) causes apoptosis of LNCaP cells as indicated by cleavage of PARP. VPC-70063 (0-500uM) disrupts the interaction of Myc-Max with DNA in a dose-dependent manner[1].

Product Categories/Family for VPC-70063, inhibitor

Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair

Structure of VPC-70063, inhibitor

VPC-70063, CAS 13571-44-3
VPC-70063 Inhibitor – Cat# MBS5785987

Structure of VPC-70063, inhibitor

VPC-70063, CAS 13571-44-3
VPC-70063 Inhibitor, Structure – Cat# MBS5785987

Product References and Citations for VPC-70063, inhibitor

1 Carabe LA e al Computer-aide dru discover o Myc-Ma inhibitor a potentia therapeutic fo prostat cancer Eu Me Chem 201 De 5 60:108-119.

Other Notes

Small volumes of VPC-70063, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VPC-70063 purchase

MBS5785987 is an inhibitor targeting VPC-70063.
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