CPSF7 Lysate – Tissue Lysate

Name: CPSF7 Lysate; Tissue Lysate; MyBioSource
Brand: MyBioSource
SKU: MBS139865
Price: 390 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS139865

Human CPSF7 Protein Lysate 20ug is provided as a Lyophilized powder.This is a Recombinant Protein Lysate produced in HEK293T cells. This protein lysate can be reconsituted using SDS Sample Buffer. More details

$390 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CPSF7, Lysate

Full Product Name

Human CPSF7 Protein Lysate

Product Gene Name

CPSF7 lysate

Product Synonym Names

CPSF7; CFIm59; CFIm59

Host

Human

Form/Format

Lyophilized

Preparation and Storage

Store at -20 degree C
Once reconsituted, aliquot and store any remaining material at-20 degree C to avoid repeated freeze-thaw cycles.

Molecular Weight

52kDa

3D Structure

ModBase 3D Structure for Q8N684

Other Notes

Small volumes of CPSF7 lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPSF7 purchase

MBS139865 is a lysate targeting CPSF7. Also known as Human CPSF7 Protein Lysate. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CPSF7. It may not necessarily be applicable to this product.

NCBI GI #

217035102

NCBI GeneID

79869

NCBI Accession #

NP_079087

UniProt Primary Accession #

Q8N684

UniProt Related Accession #

Q8N684

GenBank Nucleotide #

NM_024811

NCBI Official Full Name

cleavage and polyadenylation specificity factor subunit 7 isoform 1

NCBI Official Synonym Full Names

cleavage and polyadenylation specific factor 7

NCBI Official Symbol

CPSF7

NCBI Official Synonym Symbols

CFIm59

UniProt Protein Name

Cleavage and polyadenylation specificity factor subunit 7

UniProt Synonym Protein Names

Cleavage and polyadenylation specificity factor 59 kDa subunit; CFIm59; CPSF 59 kDa subunit; Pre-mRNA cleavage factor Im 59 kDa subunit

Protein Family

Cleavage and polyadenylation specificity factor

UniProt Gene Name

CPSF7

UniProt Synonym Gene Names

CFIm59; CPSF 59 kDa subunit

UniProt Entry Name

CPSF7_HUMAN

NCBI Protein Information

cleavage and polyadenylation specificity factor subunit 7

NCBI Summary for CPSF7

Cleavage factor Im (CFIm) is one of six factors necessary for correct cleavage and polyadenylation of pre-mRNAs. CFIm is composed of three different subunits of 25, 59, and 68 kDa, and it functions as a heterotetramer, with a dimer of the 25 kDa subunit binding to two of the 59 or 68 kDa subunits. The protein encoded by this gene represents the 59 kDa subunit, which can interact with the splicing factor U2 snRNP Auxiliary Factor (U2AF) 65 to link the splicing and polyadenylation complexes. [provided by RefSeq, Oct 2016]

UniProt Comments for CPSF7

CPSF7: probable component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3' processing. Binds to cleavage and polyadenylation RNA substrates. Probable component of the cleavage factor Im (CFIm) complex, composed at least of NUDT21/CPSF5 and CPSF6 or CPSF7. Two alternatively-spliced isoforms have been described.

Protein type: RNA splicing; RNA processing; RNA-binding

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: nucleoplasm; membrane; nucleus; mRNA cleavage factor complex

Molecular Function: protein binding; nucleotide binding

Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; protein tetramerization

Research Articles on CPSF7

1. The authors demonstrate that CFIm functions as an enhancer-dependent activator of mRNA 3' processing. CFIm regulates global alternative polyadenylation by specifically binding and activating enhancer-containing poly(A) sites.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CPSF7 lysate

Products by Pathway	Pathway Diagram
Cleavage Of Growing Transcript In The Termination Region Pathway antibodies	Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies	Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
Processing Of Capped Intronless Pre-mRNA Pathway antibodies	Processing Of Capped Intronless Pre-mRNA Pathway Diagram
Processing Of Intronless Pre-mRNAs Pathway antibodies	Processing Of Intronless Pre-mRNAs Pathway Diagram
RNA Polymerase II Transcription Pathway antibodies	RNA Polymerase II Transcription Pathway Diagram
RNA Polymerase II Transcription Termination Pathway antibodies	RNA Polymerase II Transcription Termination Pathway Diagram
MRNA 3'-end Processing Pathway antibodies	MRNA 3'-end Processing Pathway Diagram
MRNA Splicing Pathway antibodies	MRNA Splicing Pathway Diagram
MRNA Splicing - Major Pathway antibodies	MRNA Splicing - Major Pathway Diagram