GATA1 Lysate – Tissue Lysate

Name: GATA1 Lysate; Tissue Lysate; MyBioSource
Brand: MyBioSource
SKU: MBS8412126
Price: 390 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8412126

Human GATA1 Protein Lysate 20ug is provided as a Lyophilized powder.This is a Recombinant Protein Lysate produced in HEK293T cells. This protein lysate can be reconsituted using SDS Sample Buffer. More details

$390 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GATA1, Lysate

Full Product Name

Human GATA1 Protein Lysate

Product Gene Name

GATA1 lysate

Product Synonym Names

GATA1; ERYF1; GATA-1; GF-1; GF1; NF-E1; NFE1; XLANP; XLTDA; XLTT

Host

Human

Form/Format

Lyophilized

Preparation and Storage

Store at -20 degree C
Once reconsituted, aliquot and store any remaining material at-20 degree C to avoid repeated freeze-thaw cycles.

Molecular Weight

34,232 Da

OMIM

300367

3D Structure

ModBase 3D Structure for P15976

Other Notes

Small volumes of GATA1 lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GATA1 purchase

MBS8412126 is a lysate targeting GATA1. Also known as Human GATA1 Protein Lysate. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for GATA1. It may not necessarily be applicable to this product.

NCBI GI #

4503925

NCBI GeneID

2623

NCBI Accession #

NP_002040

UniProt Primary Accession #

P15976

UniProt Secondary Accession #

Q96GB8

UniProt Related Accession #

P15976

GenBank Nucleotide #

NM_002049

NCBI Official Full Name

erythroid transcription factor

NCBI Official Synonym Full Names

GATA binding protein 1 (globin transcription factor 1)

NCBI Official Symbol

GATA1

NCBI Official Synonym Symbols

GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1

UniProt Protein Name

Erythroid transcription factor

UniProt Synonym Protein Names

Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein

Protein Family

Erythroid transcription factor

UniProt Gene Name

GATA1

UniProt Synonym Gene Names

ERYF1; GF1; GATA-1; GF-1

UniProt Entry Name

GATA1_HUMAN

NCBI Protein Information

erythroid transcription factor; GATA-binding factor 1; NF-E1 DNA-binding protein; erythroid transcription factor 1; globin transcription factor 1; nuclear factor, erythroid 1; transcription factor GATA1

UniProt Comments for GATA1

GATA1: Transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. May form homodimers or heterodimers with other isoforms. Interacts (via the N-terminal zinc finger) with ZFPM1. Interacts with GFI1B. Interacts with PIAS4; the interaction enhances sumoylation and represses the transactivational activity in a sumoylation-independent manner. Interacts with LMCD1. Interacts with CREBBP; the interaction stimulates acetylation and transcriptional activity in vivo. Interacts with EP300. Erythrocytes. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: nucleoplasm; transcription factor complex; transcriptional repressor complex; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; chromatin DNA binding; p53 binding; sequence-specific DNA binding; DNA bending activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; erythrocyte development; embryonic hemopoiesis; megakaryocyte differentiation; in utero embryonic development; positive regulation of erythrocyte differentiation; eosinophil differentiation; male gonad development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; negative regulation of bone mineralization; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; positive regulation of osteoblast proliferation; erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; platelet formation; blood coagulation; basophil differentiation; negative regulation of apoptosis

Disease: Thrombocytopenia With Beta-thalassemia, X-linked; Anemia, X-linked, With Or Without Neutropenia And/or Platelet Abnormalities; Thrombocytopenia, X-linked, With Or Without Dyserythropoietic Anemia; Down Syndrome

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GATA1 lysate

Reference Product	PubMed Publications
ZFPM1 lysate	>65 publications with GATA1 and ZFPM1
LMO2 lysate	>52 publications with GATA1 and LMO2
FLI1 lysate	>28 publications with GATA1 and FLI1
STAT3 lysate	>15 publications with GATA1 and STAT3
CASP3 lysate	>8 publications with GATA1 and CASP3
ZFPM2 lysate	>7 publications with GATA1 and ZFPM2
CREBBP lysate	>6 publications with GATA1 and CREBBP
SPI1 lysate	>5 publications with GATA1 and SPI1
MED1 lysate	>4 publications with GATA1 and MED1
CEBPE lysate	>4 publications with GATA1 and CEBPE

Pathways associated with GATA1 lysate

Products by Pathway	Pathway Diagram
C-MYB Transcription Factor Network Pathway antibodies	C-MYB Transcription Factor Network Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
IL-3 Signaling Pathway antibodies	IL-3 Signaling Pathway Diagram
Notch-mediated HES/HEY Network Pathway antibodies	Notch-mediated HES/HEY Network Pathway Diagram
Signaling Events Mediated By HDAC Class I Pathway antibodies	Signaling Events Mediated By HDAC Class I Pathway Diagram
Signaling Events Mediated By HDAC Class II Pathway antibodies	Signaling Events Mediated By HDAC Class II Pathway Diagram

Diseases associated with GATA1 lysate

Disease Name	Pubmed Publications
THROMBOCYTOPENIA, X-LINKED, WITH OR WITHOUT DYSERYTHROPOIETIC ANEMIA Antibodies	>650 publications with GATA1 and THROMBOCYTOPENIA, X-LINKED, WITH OR WITHOUT DYSERYTHROPOIETIC ANEMIA
Leukemia Antibodies	>362 publications with GATA1 and Leukemia
Neoplasms Antibodies	>309 publications with GATA1 and Neoplasms
Leukemia, Myeloid, Acute Antibodies	>227 publications with GATA1 and Leukemia, Myeloid, Acute
Bone Marrow Diseases Antibodies	>195 publications with GATA1 and Bone Marrow Diseases
Down Syndrome Antibodies	>153 publications with GATA1 and Down Syndrome
Anemia Antibodies	>125 publications with GATA1 and Anemia
Thrombocytopenia Antibodies	>63 publications with GATA1 and Thrombocytopenia
Chromosome Aberrations Antibodies	>44 publications with GATA1 and Chromosome Aberrations
Disease Models, Animal Antibodies	>34 publications with GATA1 and Disease Models, Animal

Organs/Tissues associated with GATA1 lysate

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>166 publications with GATA1 and Bone Marrow
Lung Antibodies	>21 publications with GATA1 and Lung
Muscle Antibodies	>11 publications with GATA1 and Muscle
Connective Tissue Antibodies	>7 publications with GATA1 and Connective Tissue
Uncharacterized Tissue Antibodies	>1 publications with GATA1 and Uncharacterized Tissue