INPP4B Lysate – Tissue Lysate

Name: INPP4B Lysate; Tissue Lysate; MyBioSource
Brand: MyBioSource
SKU: MBS8413622
Price: 390 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8413622

Human INPP4B Protein Lysate 20ug is provided as a Lyophilized powder.This is a Recombinant Protein Lysate produced in HEK293T cells. This protein lysate can be reconsituted using SDS Sample Buffer. More details

$390 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

INPP4B, Lysate

Full Product Name

Human INPP4B Protein Lysate

Product Gene Name

INPP4B lysate

Product Synonym Names

INPP4B; MGC132014

Host

Human

Form/Format

Lyophilized

Preparation and Storage

Store at -20 degree C
Once reconsituted, aliquot and store any remaining material at-20 degree C to avoid repeated freeze-thaw cycles.

Molecular Weight

Predicted: 102 kDa
Observed: 100 kDa

OMIM

607494

3D Structure

ModBase 3D Structure for Q9BS68

Other Notes

Small volumes of INPP4B lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INPP4B purchase

MBS8413622 is a lysate targeting INPP4B. Also known as Human INPP4B Protein Lysate. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for INPP4B. It may not necessarily be applicable to this product.

NCBI GI #

156104895

NCBI GeneID

8821

NCBI Accession #

NP_003857

UniProt Primary Accession #

Q9BS68

UniProt Secondary Accession #

Q2TAI2; Q5XLE7; Q6IN59; Q6PJB4

UniProt Related Accession #

O15327

GenBank Nucleotide #

NM_003866

NCBI Official Full Name

type II inositol 3,4-bisphosphate 4-phosphatase

NCBI Official Synonym Full Names

inositol polyphosphate-4-phosphatase type II B

NCBI Official Symbol

INPP4B

UniProt Protein Name

Type II inositol 3,4-bisphosphate 4-phosphatase

UniProt Synonym Protein Names

Inositol polyphosphate 4-phosphatase type II

Protein Family

Type II inositol 3,4-bisphosphate 4-phosphatase

UniProt Gene Name

INPP4B

UniProt Entry Name

INP4B_HUMAN

NCBI Protein Information

type II inositol 3,4-bisphosphate 4-phosphatase

NCBI Summary for INPP4B

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]

UniProt Comments for INPP4B

INPP4B: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate. Widely expressed with highest levels occurring in the skeletal muscle and heart. Strongly inhibited by inositol hexakisphosphate. Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

Protein type: Carbohydrate Metabolism - inositol phosphate; Phosphatase, lipid; EC 3.1.3.66; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: cytoplasm; cytosol

Molecular Function: inositol-1,3,4-trisphosphate 4-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; protein binding

Biological Process: dephosphorylation; inositol phosphate metabolic process; phosphatidylinositol biosynthetic process; signal transduction

Research Articles on INPP4B

1. Studies in human tissues suggest that reductions in INPP4B and PTEN co-occur in human thyroid and endometrial cancers. INPP4B may therefore be an important regulator of cancer progression, especially in the context of PTEN insufficiency.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with INPP4B lysate

Products by Pathway	Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies	Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies	Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram

Organs/Tissues associated with INPP4B lysate

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>12 publications with INPP4B and Prostate
Lung Antibodies	>5 publications with INPP4B and Lung
Bone Antibodies	>4 publications with INPP4B and Bone
Nerve Antibodies	>4 publications with INPP4B and Nerve
Brain Antibodies	>3 publications with INPP4B and Brain
Liver Antibodies	>2 publications with INPP4B and Liver
Bone Marrow Antibodies	>2 publications with INPP4B and Bone Marrow
Kidney Antibodies	>2 publications with INPP4B and Kidney
Connective Tissue Antibodies	>1 publications with INPP4B and Connective Tissue
Muscle Antibodies	>1 publications with INPP4B and Muscle