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OXTR Lysate – Tissue Lysate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8416677

Human OXTR Protein Lysate 20ug is provided as a Lyophilized powder.This is a Recombinant Protein Lysate produced in HEK293T cells. This protein lysate can be reconsituted using SDS Sample Buffer. More details

$390 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
OXTR, Lysate
Full Product Name
Human OXTR Protein Lysate
Product Gene Name
OXTR lysate
Product Synonym Names
OXTR; OT-R; OT-R
Host
Human
Form/Format
Lyophilized
Preparation and Storage
Store at -20 degree C
Once reconsituted, aliquot and store any remaining material at-20 degree C to avoid repeated freeze-thaw cycles.
Molecular Weight
42 kDa
OMIM
167055
3D Structure
ModBase 3D Structure for P30559

Other Notes

Small volumes of OXTR lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OXTR purchase

MBS8416677 is a lysate targeting OXTR. Also known as Human OXTR Protein Lysate. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for OXTR. It may not necessarily be applicable to this product.

NCBI GI #
32307152
NCBI GeneID
5021
NCBI Accession #
NP_000907
UniProt Primary Accession #
P30559
UniProt Related Accession #
P30559
GenBank Nucleotide #
NM_000916
NCBI Official Full Name
oxytocin receptor
NCBI Official Synonym Full Names
oxytocin receptor
NCBI Official Symbol
OXTR
NCBI Official Synonym Symbols
OT-R
UniProt Protein Name
Oxytocin receptor
Protein Family
Oxytocin receptor
UniProt Gene Name
OXTR
UniProt Synonym Gene Names
OT-R
UniProt Entry Name
OXYR_HUMAN
NCBI Protein Information
oxytocin receptor

NCBI Summary for OXTR

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
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UniProt Comments for OXTR

OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: microvillus; cell-cell adherens junction; integral to plasma membrane; apical plasma membrane; plasma membrane

Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity

Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; maternal behavior; eating behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; G-protein coupled receptor protein signaling pathway; positive regulation of synaptogenesis; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; suckling behavior; gut development; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
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Research Articles on OXTR

1. Study provides evidence that early life adversity (ELA) is associated with lasting changes in OXTR methylation and that these changes are related to phenotypic differences in internalizing symptoms among females. This suggests that the early social environment may shape the epigenetic regulation of the OXTR gene in a way that increases risk for anxiety and depression later in life.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with OXTR lysate

 Reference Product  PubMed Publications
 OXT lysate  >62 publications with OXTR and OXT

Pathways associated with OXTR lysate

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram

Diseases associated with OXTR lysate

 Disease Name  Pubmed Publications
 Child Development Disorders, Pervasive Antibodies  >33 publications with OXTR and Child Development Disorders, Pervasive
 Autistic Disorder Antibodies  >30 publications with OXTR and Autistic Disorder
 Cognition Disorders Antibodies  >17 publications with OXTR and Cognition Disorders
 Schizophrenia Antibodies  >10 publications with OXTR and Schizophrenia
 Inflammation Antibodies  >8 publications with OXTR and Inflammation
 Depressive Disorder Antibodies  >7 publications with OXTR and Depressive Disorder
 Premature Birth Antibodies  >6 publications with OXTR and Premature Birth
 Pancreatic Neoplasms Antibodies  >4 publications with OXTR and Pancreatic Neoplasms
 Disease Models, Animal Antibodies  >4 publications with OXTR and Disease Models, Animal
 Pain Antibodies  >4 publications with OXTR and Pain

Organs/Tissues associated with OXTR lysate

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >104 publications with OXTR and Brain
 Uterus Antibodies  >28 publications with OXTR and Uterus
 Connective Tissue Antibodies  >6 publications with OXTR and Connective Tissue
 Heart Antibodies  >6 publications with OXTR and Heart
 Embryonic Tissue Antibodies  >5 publications with OXTR and Embryonic Tissue
 Ovary Antibodies  >4 publications with OXTR and Ovary
 Liver Antibodies  >3 publications with OXTR and Liver
 Lung Antibodies  >2 publications with OXTR and Lung
 Kidney Antibodies  >2 publications with OXTR and Kidney
 Skin Antibodies  >2 publications with OXTR and Skin
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