MILR1 Cell Lysate – Tissue Lysate

MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to suppress immunoglobulin E (IgE)-mediated, mast cell-dependent responses in both mice and humans. The C allele of rs6504230 was associated with increased expression of MILR1, which was following the results of expression quantitative trait loci analysis using human leukocytes. The rs6504230 polymorphism affects MILR1 expression levels in humans, leading to a susceptibility to producing specific IgE antibodies against common allergens. Diseases associated with MILR1 include Mitochondrial Dna Depletion Syndrome 16 and Autosomal Dominant Progressive External Ophthalmoplegia.

This Human Allergin 1 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of Allergin 1 protein from the overexpression lysate was verified.

Small volumes of MILR1 cell lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS8115648 is a cell lysate targeting MILR1. Also known as Human Allergin 1 HEK293 Overexpression Lysate. Host: HEK293 Cells.