Bone Marrow Proteoglycan (PRG2) ELISA Kit for Monkey

Name: Monkey PRG2 ELISA Kit; Bone Marrow Proteoglycan; MyBioSource
Brand: MyBioSource
SKU: MBS7244974
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7244974

Intended Uses: This PRG2 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Monkey PRG2. This ELISA kit for research use only! More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Bone marrow proteoglycan (PRG2), ELISA Kit

Full Product Name

Monkey Bone marrow proteoglycan (PRG2) ELISA Kit

Product Gene Name

PRG2 elisa kit

Species Reactivity

Monkey

Samples

Serum, plasma, cell culture supernatants, body fluid and tissue homogenate

Sensitivity

0.1 ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

25,206 Da

OMIM

605601

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for PRG2 elisa kit

Immunology

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of PRG2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRG2 purchase

MBS7244974 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone marrow proteoglycan (PRG2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PRG2. The ELISA analytical biochemical technique of the MBS7244974 kit is based on PRG2 antibody-PRG2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRG2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRG2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PRG2. It may not necessarily be applicable to this product.

NCBI GI #

342837699

NCBI GeneID

5553

NCBI Accession #

NP_001230174.1

UniProt Secondary Accession #

P81448; Q14227; Q6ICT2

UniProt Related Accession #

P13727

GenBank Nucleotide #

NM_001243245.1

NCBI Official Full Name

bone marrow proteoglycan isoform 2 preproprotein

NCBI Official Synonym Full Names

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

NCBI Official Symbol

PRG2

NCBI Official Synonym Symbols

MBP; BMPG; MBP1

UniProt Protein Name

Bone marrow proteoglycan

UniProt Synonym Protein Names

Proteoglycan 2Cleaved into the following chain:Eosinophil granule major basic protein; EMBP; MBPAlternative name(s):Pregnancy-associated major basic protein

Protein Family

Bone marrow proteoglycan

UniProt Gene Name

PRG2

UniProt Synonym Gene Names

MBP; BMPG; EMBP; MBP

UniProt Entry Name

PRG2_HUMAN

NCBI Protein Information

bone marrow proteoglycan; bone-marrow proteoglycan; proteoglycan 2 preproprotein; natural killer cell activator; eosinophil major basic protein; eosinophil granule major basic protein

NCBI Summary for PRG2

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

UniProt Comments for PRG2

PRG2: Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.

Protein type: Vesicle; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: transport vesicle; extracellular region

Molecular Function: heparin binding; carbohydrate binding

Biological Process: positive regulation of interleukin-4 production; negative regulation of interleukin-10 production; defense response to bacterium; immune response; defense response to nematode

Research Articles on PRG2

1. Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin-beta1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PRG2 elisa kit

Reference Product	PubMed Publications
AGT elisa kit	>2 publications with PRG2 and AGT
EPX elisa kit	>1 publications with PRG2 and EPX
PAPPA elisa kit	>1 publications with PRG2 and PAPPA

Pathways associated with PRG2 elisa kit

Products by Pathway	Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram

Diseases associated with PRG2 elisa kit

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>4 publications with PRG2 and Immune System Diseases
Hypertension Antibodies	>3 publications with PRG2 and Hypertension
Inflammation Antibodies	>3 publications with PRG2 and Inflammation
Carcinoma Antibodies	>2 publications with PRG2 and Carcinoma
Pancreatic Neoplasms Antibodies	>2 publications with PRG2 and Pancreatic Neoplasms
Lung Diseases Antibodies	>1 publications with PRG2 and Lung Diseases
Lymphoma Antibodies	>1 publications with PRG2 and Lymphoma
Ovarian Neoplasms Antibodies	>1 publications with PRG2 and Ovarian Neoplasms
Kidney Diseases Antibodies	>1 publications with PRG2 and Kidney Diseases
Lung Neoplasms Antibodies	>1 publications with PRG2 and Lung Neoplasms

Organs/Tissues associated with PRG2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>29 publications with PRG2 and Blood
Bone Marrow Antibodies	>5 publications with PRG2 and Bone Marrow
Heart Antibodies	>1 publications with PRG2 and Heart
Vascular Antibodies	>1 publications with PRG2 and Vascular
Intestine Antibodies	>1 publications with PRG2 and Intestine
Placenta Antibodies	>1 publications with PRG2 and Placenta