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CD79a Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS210648

Mouse anti Human CD79a antibody, clone ZL7-4 recognizes  the human B-cell antigen receptor complex-associated protein alpha chain, also known as MB-1 membrane glycoprotein or CD79a. clone ZL7-4 reacts with CD79a positive cells by flow cytometry and with… More details

$560 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD79a, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD79a:FITC
Product Gene Name
anti-CD79a antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
ZL7-4
Host
Mouse
Form/Format
FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration
IgG concentration 0.1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
20,786 Da
OMIM
112205
3D Structure
ModBase 3D Structure for P11912
Perservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
Immunogen
IgM complex isolated from Daudi cells
Fusion Partners||Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD79a antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD79a antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood. We recommend incubation times of at least 30 minutes with this antibody.
Flow Cytometry: Maximum Dilution: Neat

Testing Data of anti-CD79a antibody

Staining of RAMOS cells with Mouse anti Human CD79a: Alexa Fluor 488 (MBS212079A488)
Mouse Anti-CD79a Monoclonal Antibody – Cat# MBS210648

Testing Data of anti-CD79a antibody

Staining of RAMOS cells with Mouse anti Human CD79a:FITC
Mouse Anti-CD79a Monoclonal Antibody, Testing Data – Cat# MBS210648

Testing Data of anti-CD79a antibody

Staining of human peripheral blood lymphocytes with Mouse anti Human CD79a: Alexa Fluor 647 (MBS212079A647)
Mouse Anti-CD79a Monoclonal Antibody, Testing Data – Cat# MBS210648

Other Notes

Small volumes of anti-CD79a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD79a purchase

MBS210648 is an antibody targeting CD79a. Also known as MOUSE ANTI HUMAN CD79a:FITC. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD79a. It may not necessarily be applicable to this product.

NCBI GI #
4502685
NCBI GeneID
973
NCBI Accession #
NP_001774.1
UniProt Primary Accession #
P11912
UniProt Secondary Accession #
Q53FB8; A0N775
UniProt Related Accession #
P11912
GenBank Nucleotide #
NM_001783.3
NCBI Official Full Name
B-cell antigen receptor complex-associated protein alpha chain isoform 1
NCBI Official Synonym Full Names
CD79a molecule, immunoglobulin-associated alpha
NCBI Official Symbol
CD79A
NCBI Official Synonym Symbols
IGA; MB-1
UniProt Protein Name
B-cell antigen receptor complex-associated protein alpha chain
UniProt Synonym Protein Names
Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a
Protein Family
B-cell antigen receptor complex-associated protein
UniProt Gene Name
CD79A
UniProt Synonym Gene Names
IGA; MB1
UniProt Entry Name
CD79A_HUMAN
NCBI Protein Information
B-cell antigen receptor complex-associated protein alpha chain; CD79a antigen (immunoglobulin-associated alpha); MB-1 membrane glycoprotein; ig-alpha; membrane-bound immunoglobulin-associated protein; surface IgM-associated protein

NCBI Summary for CD79a

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD79a

Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; external side of plasma membrane; lipid raft

Molecular Function: transmembrane receptor activity

Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation

Disease: Agammaglobulinemia 3, Autosomal Recessive
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Research Articles on CD79a

1. Phosphorylation of CD79a causes a decrease in helical propensity in the C-terminal region, for CD79b, the opposite was observed and phosphorylation resulted in an increase of helical propensity in the C-terminal part.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD79a antibody

 Reference Product  PubMed Publications
 CD79B antibody  >616 publications with CD79a and CD79B
 CD19 antibody  >150 publications with CD79a and CD19
 PTPRC antibody  >85 publications with CD79a and PTPRC
 CD22 antibody  >69 publications with CD79a and CD22
 SYK antibody  >36 publications with CD79a and SYK
 LYN antibody  >27 publications with CD79a and LYN
 BLNK antibody  >12 publications with CD79a and BLNK
 FYN antibody  >10 publications with CD79a and FYN
 BLK antibody  >5 publications with CD79a and BLK

Pathways associated with anti-CD79a antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies  Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Signaling By The B Cell Receptor (BCR) Pathway antibodies  Signaling By The B Cell Receptor (BCR) Pathway Diagram

Diseases associated with anti-CD79a antibody

 Disease Name  Pubmed Publications
 Lymphoma Antibodies  >725 publications with CD79a and Lymphoma
 Leukemia Antibodies  >267 publications with CD79a and Leukemia
 Skin Neoplasms Antibodies  >85 publications with CD79a and Skin Neoplasms
 Neoplasms, Experimental Antibodies  >77 publications with CD79a and Neoplasms, Experimental
 Inflammation Antibodies  >45 publications with CD79a and Inflammation
 Liver Diseases Antibodies  >42 publications with CD79a and Liver Diseases
 Necrosis Antibodies  >40 publications with CD79a and Necrosis
 Hyperplasia Antibodies  >39 publications with CD79a and Hyperplasia
 Lung Diseases Antibodies  >38 publications with CD79a and Lung Diseases
 Liver Neoplasms Antibodies  >29 publications with CD79a and Liver Neoplasms

Organs/Tissues associated with anti-CD79a antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >579 publications with CD79a and Blood
 Lymph Node Antibodies  >226 publications with CD79a and Lymph Node
 Lymph Antibodies  >211 publications with CD79a and Lymph
 Spleen Antibodies  >90 publications with CD79a and Spleen
 Liver Antibodies  >83 publications with CD79a and Liver
 Lung Antibodies  >55 publications with CD79a and Lung
 Intestine Antibodies  >45 publications with CD79a and Intestine
 Thymus Antibodies  >31 publications with CD79a and Thymus
 Heart Antibodies  >28 publications with CD79a and Heart
 Mouth Antibodies  >22 publications with CD79a and Mouth
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