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Enac Beta (SCNN1B) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS191312

The epithelial sodium channel (ENaC) is a membrane-bound ion-channel that is selectively permeable to Na+ ions and that is assembled as a heterotrimer composed of three homologous subunits alpha, beta, and gamma. It is involved primarily in the reabsorption… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ENaC beta (Scnn1b), Monoclonal Antibody
Full Product Name
ENaC beta Monoclonal Antibody
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
160000
Host
Mouse
Form/Format
Protein G-purified antibody (1mg/ml) in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Preparation and Storage
This antibody is stable for at least one (1) year at-20 degree C.
Molecular Weight
71,995 Da
3D Structure
ModBase 3D Structure for Q6IRJ1
Immunogen
Synthetic peptide corresponding to C-terminal aa 617-638 of rat ENaC alpha.
Applications Tested/Suitable for anti-Scnn1b antibody
Immunoblot
Application Notes for anti-Scnn1b antibody
Immunoblot: 1ug/ml
Dilute in PBS or medium that is identical to that used in the assay system

Testing Data of anti-Scnn1b antibody

Detection of ~87kDa ENaC beta in mouse kidney homogenate at 1ug/ml.
Mouse Anti-SCNN1B Monoclonal Antibody – Cat# MBS191312

Other Notes

Small volumes of anti-Scnn1b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Scnn1b purchase

MBS191312 is an antibody targeting Scnn1b. Also known as ENaC beta Monoclonal Antibody. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Scnn1b. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
amiloride-sensitive sodium channel subunit beta
NCBI Official Synonym Full Names
sodium channel epithelial 1 beta subunit
NCBI Official Symbol
Scnn1b
NCBI Official Synonym Symbols
RNENACB
UniProt Protein Name
Amiloride-sensitive sodium channel subunit beta
UniProt Synonym Protein Names
Beta-NaCH; Epithelial Na(+) channel subunit beta; Beta-ENaC; Nonvoltage-gated sodium channel 1 subunit beta; SCNEB
UniProt Gene Name
Scnn1b
UniProt Synonym Gene Names
Beta-ENaC
NCBI Protein Information
amiloride-sensitive sodium channel subunit beta

NCBI Summary for Scnn1b

acts as an epithelial sodium ion channel; regulates salt and fluid transport in the kidney [RGD, Feb 2006]

UniProt Comments for Scnn1b

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-Scnn1b antibody

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