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GBP2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS831365

MBS831365 is an antibody targeting GBP2. Also known as GBP2 antibody. Host: Mouse. Mouse monoclonal GBP2 antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GBP2, Monoclonal Antibody
Full Product Name
GBP2 antibody
Product Gene Name
Product Synonym Names
Monoclonal GBP2; Anti-GBP2; GBP2; GBP 2; GBP-2
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
5C8
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
GBP2 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
67,209 Da
OMIM
600412
3D Structure
ModBase 3D Structure for P32456
Cross-Reactivity
Human
Immunogen
GBP2 antibody was raised in mouse using a protein expressed in 293T cell transfected with human GBP2 expression vector as the immunogen.

Product Categories/Family for anti-GBP2 antibody

Applications Tested/Suitable for anti-GBP2 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-GBP2 antibody
FC: 1:100
IF: 1:100
IHC: 1:50
WB: 1:2000

Western Blot (WB) of anti-GBP2 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GBP2 protein (Right) or empty vector (Left) detected with GBP2 antibody
Mouse Anti-GBP2 Monoclonal Antibody – Cat# MBS831365

Immunohistochemistry (IHC) of anti-GBP2 antibody

Immunohistochemical analysis of GBP2 protein in paraffin embedded Human colon tissue using GBP2 antibody
Mouse Anti-GBP2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS831365

Immunofluorescence (IF) of anti-GBP2 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant GBP2 protein using GBP2 antibody
Mouse Anti-GBP2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS831365

Other Notes

Small volumes of anti-GBP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GBP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
GBP2
NCBI Official Synonym Full Names
guanylate binding protein 2, interferon-inducible
NCBI Official Symbol
GBP2
UniProt Protein Name
Interferon-induced guanylate-binding protein 2
UniProt Synonym Protein Names
GTP-binding protein 2; GBP-2; HuGBP-2; Guanine nucleotide-binding protein 2
UniProt Gene Name
GBP2
UniProt Synonym Gene Names
GBP-2; HuGBP-2
UniProt Entry Name
GBP2_HUMAN
NCBI Protein Information
interferon-induced guanylate-binding protein 2

NCBI Summary for GBP2

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]
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UniProt Comments for GBP2

GBP2: a member of the family of large GTP-binding proteins (GBPs) that is inducible by interferon. Possesses a high GTP hydrolysis activity. GBPs are the most abundant cellular proteins expressed in response to interferon-gamma (IFN-gamma). IFN-gamma, tumor necrosis factor-alpha (TNF-alpha), and interleukin-1beta (IL-1beta) strongly induce the expression of GBP-1, -2, and -3.

Protein type: Hydrolase; Vesicle

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: Golgi membrane; cytoplasmic vesicle; cytosol; nucleus

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: defense response to Gram-positive bacterium; metabolic process; cytokine and chemokine mediated signaling pathway; adhesion to host; immune response; defense response to protozoan
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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