Mouse Anti-MBNL1 Monoclonal Antibody – Cat# MBS6207329

MBNL1 Antibody – Mouse Monoclonal

Name: MBNL1 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS6207329
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6207329

MBS6207329 is an antibody targeting MBNL1. Also known as MBNL1 (Muscleblind-like (Drosophila), DKFZp686P06174, EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL) (MaxLight 490). Host: Mouse. Mouse monoclonal antibody raised against a full length recombinant MBNL1. More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MBNL1, Monoclonal Antibody

Full Product Name

MBNL1 (Muscleblind-like (Drosophila), DKFZp686P06174, EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL) (MaxLight 490)

Product Gene Name

anti-MBNL1 antibody

Product Synonym Names

Muscleblind-like (Drosophila); DKFZp686P06174; EXP; EXP35; EXP40; EXP42; KIAA0428; MBNL

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

1D11

Host

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified

Specificity

Recognizes MBNL1.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

38kDa

3D Structure

ModBase 3D Structure for Q86VM6

Immunogen

MBNL1 (AAH50535, 1aa-343aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Conjugate

MaxLight490

Product Categories/Family for anti-MBNL1 antibody

Antibodies; RNA Processing

Applications Tested/Suitable for anti-MBNL1 antibody

Western Blot (WB)

Application Notes for anti-MBNL1 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-MBNL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MBNL1. It may not necessarily be applicable to this product.

NCBI GI #

29791635

NCBI GeneID

4154

NCBI Accession #

AAH50535

UniProt Primary Accession #

Q86VM6

UniProt Related Accession #

Q9NR56

GenBank Nucleotide #

NM_021038

NCBI Official Full Name

MBNL1 protein

NCBI Official Synonym Full Names

muscleblind like splicing regulator 1

NCBI Official Symbol

MBNL1

NCBI Official Synonym Symbols

EXP; MBNL

Protein Family

Muscleblind-like protein

NCBI Protein Information

muscleblind-like protein 1

NCBI Summary for MBNL1

This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]

Research Articles on MBNL1

1. RBFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.