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MTF1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6183712

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTF1, Monoclonal Antibody
Full Product Name
MTF1 (Metal-Regulatory Transcription Factor 1, MGC23036, MTF-1, ZRF) (PE)
Product Gene Name
Product Synonym Names
Metal-Regulatory Transcription Factor 1; MGC23036; MTF-1; ZRF
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2C12
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified
Specificity
Recognizes MTF1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
81kDa
OMIM
600172
3D Structure
ModBase 3D Structure for Q14872
Immunogen
MTF1 (NP_005946, 41aa-140aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
GTVYDRTTVLIEQDPGTLEDEDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRY
Conjugate
PE
Applications Tested/Suitable for anti-MTF1 antibody
Western Blot (WB)
Application Notes for anti-MTF1 antibody
Applications are based on unconjugated antibody.

Testing Data of anti-MTF1 antibody

Detection limit for recombinant GST tagged MTF1 is approximately 0.03ng/ml as a capture antibody.
Mouse Anti-MTF1 Monoclonal Antibody – Cat# MBS6183712

Other Notes

Small volumes of anti-MTF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTF1 purchase

MBS6183712 is an antibody targeting MTF1. Also known as MTF1 (Metal-Regulatory Transcription Factor 1, MGC23036, MTF-1, ZRF) (PE). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MTF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
metal regulatory transcription factor 1
NCBI Official Synonym Full Names
metal regulatory transcription factor 1
NCBI Official Symbol
MTF1
NCBI Official Synonym Symbols
ZRF; MTF-1
UniProt Protein Name
Metal regulatory transcription factor 1
UniProt Synonym Protein Names
MRE-binding transcription factor; Transcription factor MTF-1
UniProt Gene Name
MTF1
UniProt Entry Name
MTF1_HUMAN
NCBI Protein Information
metal regulatory transcription factor 1

UniProt Comments for MTF1

MTF1: Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).

Protein type: Transcription factor; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 1p33

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding; histone acetyltransferase binding; metal ion binding; protein binding; transcription coactivator activity; transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; response to cadmium ion; response to metal ion; response to oxidative stress; transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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