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PDE3A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6177079

MBS6177079 is an antibody targeting PDE3A. Also known as PDE3A (Phosphodiesterase 3A, cGMP-inhibited, CGI-PDE) (FITC). Host: Mouse. Mouse monoclonal antibody raised against a partial recombinant PDE3A. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDE3A, Monoclonal Antibody
Full Product Name
PDE3A (Phosphodiesterase 3A, cGMP-inhibited, CGI-PDE) (FITC)
Product Gene Name
Product Synonym Names
Phosphodiesterase 3A; cGMP-inhibited; CGI-PDE
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
2D7
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified
Specificity
Recognizes PDE3A.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.

FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
124,979 Da
OMIM
123805. gene.
3D Structure
ModBase 3D Structure for Q14432
Immunogen
PDE3A (NP_000912, 533aa-640aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
TPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNE
Conjugate
FITC
Applications Tested/Suitable for anti-PDE3A antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-PDE3A antibody
Applications are based on unconjugated antibody.

Testing Data of anti-PDE3A antibody

Detection limit for recombinant GST tagged PDE3A is 0.1 ng/ml as a capture antibody.
Mouse Anti-PDE3A Monoclonal Antibody – Cat# MBS6177079

Immunofluorescence (IF) of anti-PDE3A antibody

Immunofluorescence of monoclonal antibody to PDE3A on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-PDE3A Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6177079

Immunofluorescence (IF) of anti-PDE3A antibody

Immunofluorescence of monoclonal antibody to PDE3A on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-PDE3A Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6177079

Other Notes

Small volumes of anti-PDE3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDE3A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform 1
NCBI Official Synonym Full Names
phosphodiesterase 3A, cGMP-inhibited
NCBI Official Symbol
PDE3A
NCBI Official Synonym Symbols
HTNB; CGI-PDE; CGI-PDE A; CGI-PDE-A
UniProt Protein Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase A
UniProt Synonym Protein Names
Cyclic GMP-inhibited phosphodiesterase A
UniProt Gene Name
PDE3A
UniProt Entry Name
PDE3A_HUMAN
NCBI Protein Information
cGMP-inhibited 3',5'-cyclic phosphodiesterase A

NCBI Summary for PDE3A

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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