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PTPN7 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS837888

MBS837888 is an antibody targeting PTPN7. Also known as PTPN7 antibody. Host: Mouse. Mouse monoclonal PTPN7 antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTPN7, Monoclonal Antibody
Full Product Name
PTPN7 antibody
Product Gene Name
anti-PTPN7 antibody
Product Synonym Names
Monoclonal PTPN7; Anti-PTPN7; Protein tyrosine phosphatase non-receptor type 7; HEPTP; LC-PTP; Hematopoietic protein-tyrosine phosphatase; BPTP4; FLJ18703; LPTP; PTPN7; PTPN 7; PTPN-7
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
3B10
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
PTPN7 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
40,351 Da
Cross-Reactivity
Human, Dog, Rat, Mouse
Immunogen
PTPN7 antibody was raised in mouse using a full length recombinant protein of human PTPN7 (NP_542155) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-PTPN7 antibody

Signal Transduction
Applications Tested/Suitable for anti-PTPN7 antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-PTPN7 antibody
IF: 1:100
WB: 1:500-2000

Immunofluorescence (IF) of anti-PTPN7 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant PTPN7 protein using PTPN7 antibody
Mouse Anti-PTPN7 Monoclonal Antibody – Cat# MBS837888

Western Blot (WB) of anti-PTPN7 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PTPN7 protein (Right) or empty vector (Left) detected with PTPN7 antibody
Mouse Anti-PTPN7 Monoclonal Antibody, Western Blot (WB) – Cat# MBS837888

Other Notes

Small volumes of anti-PTPN7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN7. It may not necessarily be applicable to this product.

NCBI GI #
68534220
NCBI GeneID
320139
NCBI Accession #
AAH98475.1
UniProt Related Accession #
Q8BUM3
NCBI Official Full Name
Ptpn7 protein
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 7
NCBI Official Symbol
Ptpn7
NCBI Official Synonym Symbols
LPTP; HEPTP; BPTP-4; LC-PTP; C920001D21Rik
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 7
UniProt Synonym Protein Names
Hematopoietic protein-tyrosine phosphatase; HEPTP
Protein Family
Tyrosine-protein phosphatase non-receptor
UniProt Gene Name
Ptpn7
UniProt Synonym Gene Names
HEPTP
UniProt Entry Name
PTN7_MOUSE
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 7

UniProt Comments for PTPN7

HePTP: a non-receptor protein-tyrosine phosphatase. Preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. Its noncatalytic N-terminus can interact with MAP kinases and suppress the MAP kinase activities. Shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Three alternatively spliced transcript variants of this gene, which encode two distinct isoforms, are reported. May play a role in the regulation of lymphocyte development.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor)

Cellular Component: internal side of plasma membrane; cytoskeleton; cytoplasm; cytosol

Molecular Function: hydrolase activity; phosphoric monoester hydrolase activity; protein tyrosine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: dephosphorylation; protein amino acid dephosphorylation
Show more

Research Articles on PTPN7

1. PTPN7 as a negative regulator of TNF-alpha expression and the inflammatory response in macrophages

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTPN7 antibody

 Reference Product  PubMed Publications
 Mapk1 antibody  >10 publications with PTPN7 and Mapk1
 Mapk3 antibody  >5 publications with PTPN7 and Mapk3
 Mapk14 antibody  >3 publications with PTPN7 and Mapk14

Pathways associated with anti-PTPN7 antibody

 Products by Pathway  Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram

Diseases associated with anti-PTPN7 antibody

 Disease Name  Pubmed Publications
 Leukemia Antibodies  >4 publications with PTPN7 and Leukemia
 Inflammation Antibodies  >4 publications with PTPN7 and Inflammation
 Necrosis Antibodies  >2 publications with PTPN7 and Necrosis
 Weight Loss Antibodies  >1 publications with PTPN7 and Weight Loss
 Death Antibodies  >1 publications with PTPN7 and Death

Organs/Tissues associated with anti-PTPN7 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with PTPN7 and Blood
 Lung Antibodies  >1 publications with PTPN7 and Lung
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