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ADAMTS13 Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9436690

ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)also known as von Willebrand factor-cleaving protease (VWFCP)is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ADAMTS13, Monoclonal Antibody
Full Product Name
ADAMTS13 Antibody
Product Gene Name
Product Synonym Names
A disintegrin and metalloproteinase with thrombospondin motifs 13 antibody; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 13 antibody; A disintegrin like and metalloprotease with thrombospondin type 1 motif 13 antibody; ADAM metallopeptidase with thrombospondin type 1 motif 13 antibody; ADAM TS antibody; ADAM-TS 13 antibody; ADAM-TS13 antibody; ADAMTS 13 antibody; ADAMTS-13 antibody; ADAMTS13 antibody; ADAMTS13 protein antibody; ATS13_HUMAN antibody; C9orf8 antibody; TTP antibody; Von Willebrand factor cleaving protease antibody; von Willebrand factor-cleaving protease antibody; vWF cleaving protease antibody; vWF CP antibody; vWF-cleaving protease antibody; vWF-CP antibody; vWFCP antibody
Clonality
Monoclonal
Clone Number
JG39-21
Host
Rabbit
Species Reactivity
Human
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Purity/Purification
ProA affinity purified
Preparation and Storage
Store at -20 degree C.
Molecular Weight
147,804 Da
3D Structure
ModBase 3D Structure for Q76LX8
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein within human ADAMTS13 aa 150-350.
Conjugation
Unconjugated

Product Categories/Family for anti-ADAMTS13 antibody

Applications Tested/Suitable for anti-ADAMTS13 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-ADAMTS13 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
FC/FACS: 1:50-1:100

Western Blot (WB) of anti-ADAMTS13 antibody

Western blot analysis of ADAMTS13 on SiHa cell (1), PC-3M cell (2) and A549 cell lysates using anti-ADAMTS13 antibody at 1/500 dilution.
Rabbit Anti-ADAMTS13 Monoclonal Antibody – Cat# MBS9436690

Immunohistochemistry (IHC) of anti-ADAMTS13 antibody

Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ADAMTS13 antibody. Counter stained with hematoxylin.
Rabbit Anti-ADAMTS13 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9436690

Immunohistochemistry (IHC) of anti-ADAMTS13 antibody

Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-ADAMTS13 antibody. Counter stained with hematoxylin.
Rabbit Anti-ADAMTS13 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9436690

Flow Cytometry (FC/FACS) of anti-ADAMTS13 antibody

Flow cytometric analysis of HepG2 cells with ADAMTS13 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Rabbit Anti-ADAMTS13 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS9436690

Other Notes

Small volumes of anti-ADAMTS13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADAMTS13 purchase

MBS9436690 is an antibody targeting ADAMTS13. Also known as ADAMTS13 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ADAMTS13. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform 2 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 13
NCBI Official Symbol
ADAMTS13
NCBI Official Synonym Symbols
VWFCP; C9orf8; vWF-CP; ADAM-TS13; ADAMTS-13
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 13
UniProt Synonym Protein Names
von Willebrand factor-cleaving protease; vWF-CP; vWF-cleaving protease
UniProt Gene Name
ADAMTS13
UniProt Synonym Gene Names
C9orf8; ADAM-TS 13; ADAM-TS13; ADAMTS-13; vWF-CP; vWF-cleaving protease
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 13

NCBI Summary for ADAMTS13

This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for ADAMTS13

Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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