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CD81 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2556503

CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CD81, Monoclonal Antibody
Full Product Name
Anti-Human CD81 Monoclonal Antibody (Alexa Fluor 488 Conjugated)
Product Gene Name
Product Synonym Names
CD81 antigen; CD81; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1.Tetraspanin-28; Tspan-28; APA1; TSPAN28
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1.3.3.22
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Preparation and Storage
Store at 2-8 degree C and protect from prolonged exposure to light. Do not freeze.
Matching Pairs
Molecular Weight
25,809 Da
3D Structure
ModBase 3D Structure for P60033
Conjugation
Alexa Fluor 488
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD81 antibody
Flow Cytometry (FC/FACS)

Flow Cytometry (FC/FACS) of anti-CD81 antibody

Human peripheral blood lymphocytes are stained with Anti-Human CD81 Monoclonal Antibody (Alexa Fluor 488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Mouse Anti-CD81 Monoclonal Antibody – Cat# MBS2556503

Product References and Citations for anti-CD81 antibody

1. Menno C, et al. 2010. J. Clin. Invest. 4:1265. 2. Fearon D, et al. 1995. Annu. Rev. Immunol. 13:127. 3. Wright M, et al. 1994. Immunol. Today 15:588.

Other Notes

Small volumes of anti-CD81 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD81 purchase

MBS2556503 is an antibody targeting CD81. Also known as Anti-Human CD81 Monoclonal Antibody (Alexa Fluor 488 Conjugated). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD81. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CD81 antigen isoform 2
NCBI Official Synonym Full Names
CD81 molecule
NCBI Official Symbol
CD81
NCBI Official Synonym Symbols
S5.7; CVID6; TAPA1; TSPAN28
UniProt Protein Name
CD81 antigen
UniProt Synonym Protein Names
26 kDa cell surface protein TAPA-1
Protein Family
UniProt Gene Name
CD81
UniProt Synonym Gene Names
TAPA11 PublicationManual assertion based on opinion iniRef.1; Tspan-28
NCBI Protein Information
CD81 antigen

NCBI Summary for CD81

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
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UniProt Comments for CD81

May be involved in the acrosome reaction (). May play an important role in the regulation of lymphoma cell growth (PubMed:1695320, PubMed:2398277).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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