Mouse Anti-IL8 Monoclonal Antibody – Cat# MBS8533048

IL8 Antibody – Mouse Monoclonal

Name: IL8 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8533048
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8533048

$380 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL8, Monoclonal Antibody

Full Product Name

Anti-IL8 Mouse mAb

Product Gene Name

anti-IL8 antibody

Product Synonym Names

(Ala-IL-8)77; (Ser-IL-8)72; 3 10C; 310C; AMCF 1; AMCF1; b ENAP; Bbeta thromboglobulin like protein; Beta thromboglobulin like protein; C-X-C motif chemokine 8; CXC chemokine ligand 8; CXCL 8; CXCL8; Emoctakin; GCP 1; GCP-1; GCP/IL-8 protein I; GCP/IL-8 protein II; GCP/IL-8 protein III; GCP/IL-8 protein IV; GCP/IL-8 protein V; GCP/IL-8 protein VI; GCP1; Granulocyte chemotactic protein 1; IL 8; IL-8; IL-8(1-77); IL-8(9-77); IL8; IL8/NAP1 form I; IL8/NAP1 form II; IL8/NAP1 form III; IL8/NAP1 form IV; IL8/NAP1 form V; IL8/NAP1 form VI; IL8_HUMAN; Inteleukin 8; Interleukin8; K 60; K60; LECT; LUCT; Lymphocyte derived neutrophil activating factor; Lymphocyte-derived neutrophil-activating factor; LYNAP; MDNCF; MDNCF-b; MDNCF-c; MONAP; Monocyte derived neutrophil activating peptide; Monocyte derived neutrophil activating protein; Monocyte derived neutrophil chemotactic factor; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; NAF; NAP 1; NAP-1; NAP1; Neutrophil activating factor; Neutrophil activating peptide 1; Neutrophil activating protein 1; Neutrophil-activating factor; Neutrophil-activating protein 1; Protein 3 10C; Protein 3-10C; SCYB 8; SCYB8; Small inducible cytokine subfamily B member 8; T cell chemotactic factor; T-cell chemotactic factor; TSG 1; TSG1

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

6E7-C11-C9

Host

Mouse

Species Reactivity

Human

Form/Format

PBS (pH 7.4) containing 0.02% sodium azide and 50% glycerol.

Purity/Purification

Affinity purified

Preparation and Storage

Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.

OMIM

146930

3D Structure

ModBase 3D Structure for P10145

Immunogen

Purified recombinant human IL8 protein fragments expressed in E Coli.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-IL8 antibody

Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of anti-IL8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL8 purchase

MBS8533048 is an antibody targeting IL8. Also known as Anti-IL8 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL8. It may not necessarily be applicable to this product.

NCBI GI #

10834978

NCBI GeneID

3576

NCBI Accession #

NP_000575.1

UniProt Primary Accession #

P10145

UniProt Secondary Accession #

Q6FGF6; Q6LAE6; Q96RG6; Q9C077; Q9UCE1; Q9UCR8; Q9UCR9; Q9UCS0; B2R4L8

UniProt Related Accession #

P10145

GenBank Nucleotide #

NM_000584

NCBI Official Full Name

interleukin-8 isoform 1

NCBI Official Synonym Full Names

C-X-C motif chemokine ligand 8

NCBI Official Symbol

CXCL8

NCBI Official Synonym Symbols

IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1

UniProt Protein Name

Interleukin-8

UniProt Synonym Protein Names

C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1

Protein Family

G-protein coupled estrogen receptor

UniProt Gene Name

CXCL8

UniProt Synonym Gene Names

IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF

NCBI Protein Information

interleukin-8

NCBI Summary for IL8

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the site of infection. This chemokine is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q. [provided by RefSeq, Aug 2017]

UniProt Comments for IL8

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

Research Articles on IL8

1. STAT1 knockdown using an inhibitor and siRNA attenuated the IL-17-mediated increases in IL-6, IL-8 and VEGF expression in A549 and H292 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL8 antibody

Products by Pathway	Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Activation Of Genes By ATF4 Pathway antibodies	Activation Of Genes By ATF4 Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies	Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram

Diseases associated with anti-IL8 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>675 publications with IL8 and Inflammation
Necrosis Antibodies	>395 publications with IL8 and Necrosis
Hypersensitivity Antibodies	>66 publications with IL8 and Hypersensitivity
Drug Toxicity Antibodies	>62 publications with IL8 and Drug Toxicity
Adenocarcinoma Antibodies	>49 publications with IL8 and Adenocarcinoma
Pulmonary Disease, Chronic Obstructive Antibodies	>48 publications with IL8 and Pulmonary Disease, Chronic Obstructive
Pneumonia Antibodies	>34 publications with IL8 and Pneumonia
Colorectal Neoplasms Antibodies	>30 publications with IL8 and Colorectal Neoplasms
Kidney Diseases Antibodies	>27 publications with IL8 and Kidney Diseases
Breast Neoplasms Antibodies	>26 publications with IL8 and Breast Neoplasms

Organs/Tissues associated with anti-IL8 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>669 publications with IL8 and Blood
Lung Antibodies	>237 publications with IL8 and Lung
Vascular Antibodies	>201 publications with IL8 and Vascular
Intestine Antibodies	>90 publications with IL8 and Intestine
Skin Antibodies	>81 publications with IL8 and Skin
Liver Antibodies	>71 publications with IL8 and Liver
Heart Antibodies	>67 publications with IL8 and Heart
Bone Antibodies	>60 publications with IL8 and Bone
Muscle Antibodies	>59 publications with IL8 and Muscle
Brain Antibodies	>48 publications with IL8 and Brain