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MAPRE3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6137524

Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MAPRE3, Monoclonal Antibody
Full Product Name
MAPRE3 (Microtubule-associated Protein RP/EB Family Member 3, EB1 Protein Family Member 3, EBF3, End-binding Protein 3, EB3, RP3) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3D7
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human MAPRE3.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
34.1 kDa (301aa)) confirmed by MALDI-TOF
OMIM
605788
3D Structure
ModBase 3D Structure for Q9UPY8
Immunogen
Partial recombinant corresponding to aa125-219 from MAPRE3 (NP_036458) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
NPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDG*
Conjugate
APC

Product Categories/Family for anti-MAPRE3 antibody

Applications Tested/Suitable for anti-MAPRE3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-MAPRE3 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-MAPRE3 antibody

Western Blot detection against Immunogen (36.45kD).
Mouse Anti-MAPRE3 Monoclonal Antibody – Cat# MBS6137524

Testing Data of anti-MAPRE3 antibody

Detection limit for recombinant GST tagged MAPRE3 is 0.3ng/ml as a capture antibody.
Mouse Anti-MAPRE3 Monoclonal Antibody, Testing Data – Cat# MBS6137524

Other Notes

Small volumes of anti-MAPRE3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAPRE3 purchase

MBS6137524 is an antibody targeting MAPRE3. Also known as MAPRE3 (Microtubule-associated Protein RP/EB Family Member 3, EB1 Protein Family Member 3, EBF3, End-binding Protein 3, EB3, RP3) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MAPRE3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
microtubule-associated protein RP/EB family member 3
NCBI Official Synonym Full Names
microtubule associated protein RP/EB family member 3
NCBI Official Symbol
MAPRE3
NCBI Official Synonym Symbols
EB3; RP3; EBF3; EBF3-S
UniProt Protein Name
Microtubule-associated protein RP/EB family member 3
UniProt Synonym Protein Names
EB1 protein family member 3; EBF3; End-binding protein 3; EB3; RP3
UniProt Gene Name
MAPRE3
UniProt Synonym Gene Names
EBF3; EB3
UniProt Entry Name
MARE3_HUMAN
NCBI Protein Information
microtubule-associated protein RP/EB family member 3

NCBI Summary for MAPRE3

The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]

UniProt Comments for MAPRE3

EB3: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. Belongs to the MAPRE family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding

Chromosomal Location of Human Ortholog: 2p23.3-p23.1

Cellular Component: microtubule cytoskeleton; cytoplasmic microtubule; perinuclear region of cytoplasm; cytoplasm; midbody

Molecular Function: protein binding; microtubule binding

Biological Process: mitosis; positive regulation of cyclin-dependent protein kinase activity; cell division; positive regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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