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MTUS1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6137728

Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation,… More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTUS1, Monoclonal Antibody
Full Product Name
MTUS1 (Microtubule-associated Tumor Suppressor 1, AT2 Receptor-binding Protein, Angiotensin-II Type 2 Receptor-interacting Protein, Mitochondrial Tumor Suppressor 1, ATBP, ATIP, GK1, KIAA1288, MTSG1, DKFZp586D1519, DKFZp686F20243, FLJ14295, KIAA1288) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1C7
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human MTUS1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
48,050 Da
Immunogen
Full length recombinant corresponding to aa1-241 from human MTUS1 (AAH33842) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MQLQEQFDNLNAAHETSKLEIEASHSEKLELLTKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMGKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPLQSPRNSGSFPSPSISPR
Conjugate
APC

Product Categories/Family for anti-MTUS1 antibody

Applications Tested/Suitable for anti-MTUS1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-MTUS1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-MTUS1 antibody

Western Blot detection against Immunogen (52.51kD).
Mouse Anti-MTUS1 Monoclonal Antibody – Cat# MBS6137728

Western Blot (WB) of anti-MTUS1 antibody

MTUS1 monoclonal antibody. Western Blot analysis of MTUS1 expression in human colon.
Mouse Anti-MTUS1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6137728

Testing Data of anti-MTUS1 antibody

Detection limit for recombinant GST tagged MTUS1 is ~0.3ng/ml as a capture antibody.
Mouse Anti-MTUS1 Monoclonal Antibody, Testing Data – Cat# MBS6137728

Other Notes

Small volumes of anti-MTUS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTUS1 purchase

MBS6137728 is an antibody targeting MTUS1. Also known as MTUS1 (Microtubule-associated Tumor Suppressor 1, AT2 Receptor-binding Protein, Angiotensin-II Type 2 Receptor-interacting Protein, Mitochondrial Tumor Suppressor 1, ATBP, ATIP, GK1, KIAA1288, MTSG1, DKFZp586D1519, DKFZp686F20243, FLJ14295, KIAA1288) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MTUS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens mitochondrial tumor suppressor 1, mRNA
NCBI Official Synonym Full Names
microtubule associated tumor suppressor 1
NCBI Official Symbol
MTUS1
NCBI Official Synonym Symbols
ATBP; ATIP; ICIS; MP44; MTSG1
NCBI Protein Information
microtubule-associated tumor suppressor 1

NCBI Summary for MTUS1

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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