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NOVA1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6159139

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NOVA1, Monoclonal Antibody
Full Product Name
NOVA1 (RNA-Binding Protein Nova-1, Neuro-oncological Ventral Antigen 1, Onconeural Ventral Antigen 1, Nova-1, Paraneoplastic Ri Antigen, Ventral Neuron-specific Protein 1) (PE)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3F3
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human NOVA1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
49,253 Da
OMIM
602157
3D Structure
ModBase 3D Structure for P51513
Immunogen
Partial recombinant corresponding to aa408-508 from human NOVA1 (NP_002506) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG
Conjugate
PE
Applications Tested/Suitable for anti-NOVA1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-NOVA1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-NOVA1 antibody

Western Blot detection against Immunogen (36.52kD).
Mouse Anti-NOVA1 Monoclonal Antibody – Cat# MBS6159139

Western Blot (WB) of anti-NOVA1 antibody

NOVA1 monoclonal antibody. Western Blot analysis of NOVA1 expression in IMR-32.
Mouse Anti-NOVA1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6159139

Other Notes

Small volumes of anti-NOVA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NOVA1 purchase

MBS6159139 is an antibody targeting NOVA1. Also known as NOVA1 (RNA-Binding Protein Nova-1, Neuro-oncological Ventral Antigen 1, Onconeural Ventral Antigen 1, Nova-1, Paraneoplastic Ri Antigen, Ventral Neuron-specific Protein 1) (PE). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NOVA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
RNA-binding protein Nova-1 isoform 1
NCBI Official Synonym Full Names
neuro-oncological ventral antigen 1
NCBI Official Symbol
NOVA1
NCBI Official Synonym Symbols
Nova-1
UniProt Protein Name
RNA-binding protein Nova-1
UniProt Synonym Protein Names
Neuro-oncological ventral antigen 1; Onconeural ventral antigen 1; Paraneoplastic Ri antigen; Ventral neuron-specific protein 1
Protein Family
UniProt Gene Name
NOVA1
UniProt Entry Name
NOVA1_HUMAN
NCBI Protein Information
RNA-binding protein Nova-1; onconeural ventral antigen 1; paraneoplastic Ri antigen; ventral neuron-specific protein 1

UniProt Comments for NOVA1

NOVA1: May regulate RNA splicing or metabolism in a specific subset of developing neurons. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 14q

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: mRNA binding; RNA binding

Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; synaptic transmission; regulation of RNA metabolic process; RNA splicing; locomotory behavior
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NOVA1 antibody

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