• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PLGF Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6123609

MBS6123609 is an antibody targeting PLGF. Also known as PLGF (PGFL, PIGF, placental growth factor (PGF), PlGF2, Vascular endothelial growth factor related protein) (PE). Reactive in Human. Host: Mouse. More details

$1105 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLGF, Monoclonal Antibody
Full Product Name
PLGF (PGFL, PIGF, placental growth factor (PGF), PlGF2, Vascular endothelial growth factor related protein) (PE)
Product Gene Name
anti-PLGF antibody
Product Synonym Names
PGFL; PIGF; placental growth factor (PGF); PlGF2; Vascular endothelial growth factor related protein
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
PLGF94
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Specificity
Recognizes human PLGF.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
24,789 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (75408533..75422467, complement). Location: 14q24.3
OMIM
601121
3D Structure
ModBase 3D Structure for P49763
Immunogen
Recombinant human PLGF protein. Cellular Localization: Secreted (extracellular)
Conjugate
PE
Positive Control
HepG2 cells or human placental and brain tumors
Special Handling
Light sensitive

Product Categories/Family for anti-PLGF antibody

Antibodies; Growth Factors; Cytokines
Applications Tested/Suitable for anti-PLGF antibody
FLISA
Application Notes for anti-PLGF antibody
Applications are based on unconjugated antibody.

Product References and Citations for anti-PLGF antibody

1. Beiswenger TR et al. The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin. Reprod Sci 19:526-33 (2012). 2. Xu HX et al. Expression and prognostic significance of placental growth factor in hepatocellular carcinoma and peritumoral liver tissue. Int J Cancer 128:1559-69 (2011).

Other Notes

Small volumes of anti-PLGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLGF. It may not necessarily be applicable to this product.

NCBI GI #
333033785
NCBI GeneID
5228
NCBI Accession #
NP_001193941.1
UniProt Primary Accession #
P49763
UniProt Secondary Accession #
Q07101; Q9BV78; Q9Y6S8
UniProt Related Accession #
P49763
GenBank Nucleotide #
NM_001207012.1
NCBI Official Full Name
placenta growth factor isoform 2
NCBI Official Synonym Full Names
placental growth factor
NCBI Official Symbol
PGF
NCBI Official Synonym Symbols
PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
UniProt Protein Name
Placenta growth factor
Protein Family
Placenta growth factor
UniProt Gene Name
PGF
UniProt Synonym Gene Names
PGFL; PLGF; PlGF
UniProt Entry Name
PLGF_HUMAN
NCBI Protein Information
placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein

NCBI Summary for PLGF

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

UniProt Comments for PLGF

PGF: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: heparin binding; protein binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity

Biological Process: response to drug; organ regeneration; female pregnancy; signal transduction; cellular response to hormone stimulus; positive regulation of angiogenesis; cell-cell signaling; ureteric bud branching; positive regulation of cell division; positive regulation of cell proliferation; response to hypoxia; positive regulation of endothelial cell proliferation; sprouting angiogenesis; vascular endothelial growth factor receptor signaling pathway; cell differentiation
Show more

Research Articles on PLGF

1. Placental growth factor has a role in adverse outcomes in patients with suspected preeclampsia or intrauterine growth restriction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLGF antibody

 Reference Product  PubMed Publications
 VEGFA antibody  >20 publications with PLGF and VEGFA
 FLT1 antibody  >15 publications with PLGF and FLT1
 IL6 antibody  >12 publications with PLGF and IL6
 KDR antibody  >8 publications with PLGF and KDR
 FLT4 antibody  >2 publications with PLGF and FLT4
 AKT1 antibody  >1 publications with PLGF and AKT1
 PIK3CA antibody  >1 publications with PLGF and PIK3CA
 NRP1 antibody  >1 publications with PLGF and NRP1

Pathways associated with anti-PLGF antibody

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By VEGF Pathway antibodies  Signaling By VEGF Pathway Diagram
 VEGF Binds To VEGFR Leading To Receptor Dimerization Pathway antibodies  VEGF Binds To VEGFR Leading To Receptor Dimerization Pathway Diagram
 VEGF Ligand-receptor Interactions Pathway antibodies  VEGF Ligand-receptor Interactions Pathway Diagram

Diseases associated with anti-PLGF antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >369 publications with PLGF and Cardiovascular Diseases
 Inflammation Antibodies  >274 publications with PLGF and Inflammation
 Hypertension Antibodies  >191 publications with PLGF and Hypertension
 Disease Models, Animal Antibodies  >155 publications with PLGF and Disease Models, Animal
 Neoplasms Antibodies  >150 publications with PLGF and Neoplasms
 Necrosis Antibodies  >148 publications with PLGF and Necrosis
 Heart Diseases Antibodies  >123 publications with PLGF and Heart Diseases
 Atherosclerosis Antibodies  >89 publications with PLGF and Atherosclerosis
 Drug Toxicity Antibodies  >80 publications with PLGF and Drug Toxicity
 Brain Diseases Antibodies  >69 publications with PLGF and Brain Diseases

Organs/Tissues associated with anti-PLGF antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >748 publications with PLGF and Ovary
 Uterus Antibodies  >720 publications with PLGF and Uterus
 Muscle Antibodies  >497 publications with PLGF and Muscle
 Heart Antibodies  >241 publications with PLGF and Heart
 Lung Antibodies  >233 publications with PLGF and Lung
 Kidney Antibodies  >210 publications with PLGF and Kidney
 Placenta Antibodies  >199 publications with PLGF and Placenta
 Embryonic Tissue Antibodies  >195 publications with PLGF and Embryonic Tissue
 Brain Antibodies  >194 publications with PLGF and Brain
 Liver Antibodies  >133 publications with PLGF and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000