Mouse Anti-PP32 Monoclonal Antibody – Cat# MBS9602426

Figure 1: Western blot analysis using PP32 mouse mAb against Hela (1) cell lysate.

PP32 Antibody – Mouse Monoclonal

Name: PP32 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9602426
Price: 325 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9602426

Function: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PP32, Monoclonal Antibody

Full Product Name

PP32 Antibody

Product Gene Name

anti-PP32 antibody

Product Synonym Names

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; Acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic nuclear phosphoprotein 32 family member A; Acidic nuclear phosphoprotein pp32; AN32A_HUMAN; ANP32A; C15orf1; Cerebellar leucine rich acidic nuclear protein; Hepatopoietin Cn; HPPCn; I1PP2A; Inhibitor 1 of protein phosphatase 2A; inhibitor-1 of protein phosphatase-2A; Lanp; Leucine rich acidic nuclear protein; Leucine-rich acidic nuclear protein; MAPM; Mapmodulin; MGC119787; MGC150373; PHAPI; Potent heat stable protein phosphatase 2A inhibitor I1PP2A; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; PP32; Putative HLA DR associated protein I; Putative HLA-DR-associated protein I; Putative human HLA class II associated protein I; Putative human HLA class II-associated protein

Clonality

Monoclonal

Isotype

IgG1

Host

Mouse

Species Reactivity

Human

Form/Format

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purity/Purification

Affinity-Chromatography

Concentration

1mg/ml (lot specific)

Specificity

PP32 antibody detects endogenous levels of total PP32

Preparation and Storage

Store at -20 degree C. Stable for 12 months from date of receipt.

Molecular Weight

Observed: 28 kDa
Predicted: 29 kDa

3D Structure

ModBase 3D Structure for P39687

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Immunogen

Purified recombinant fragment of human PP32 expressed in E. Coli

Subcellular Location

Nucleus. Cytoplasm. Endoplasmic Reticulum. Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm.

Tissue Specificity

Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PP32 antibody

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

Application Notes for anti-PP32 antibody

ELISA: 1:10000
WB: 1:500-1:2000
IHC: 1:200-1:1000

Other Notes

Small volumes of anti-PP32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PP32 purchase

MBS9602426 is an antibody targeting PP32. Also known as PP32 Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PP32. It may not necessarily be applicable to this product.

NCBI GI #

5453880

NCBI GeneID

8125

NCBI Accession #

NP_006296.1

UniProt Primary Accession #

P39687

UniProt Secondary Accession #

Q53FK4; Q5J8L8; Q7M4N6; B2R6T4

UniProt Related Accession #

P39687

GenBank Nucleotide #

NM_006305.3

NCBI Official Full Name

acidic leucine-rich nuclear phosphoprotein 32 family member A

NCBI Official Synonym Full Names

acidic nuclear phosphoprotein 32 family member A

NCBI Official Symbol

ANP32A

NCBI Official Synonym Symbols

LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1

UniProt Protein Name

Acidic leucine-rich nuclear phosphoprotein 32 family member A

UniProt Synonym Protein Names

Acidic nuclear phosphoprotein pp32; pp32; Leucine-rich acidic nuclear protein; LANP; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA-DR-associated protein I; PHAPI

UniProt Gene Name

ANP32A

UniProt Synonym Gene Names

C15orf1; LANP; MAPM; PHAP1; pp32; LANP; PHAPI

NCBI Protein Information

acidic leucine-rich nuclear phosphoprotein 32 family member A

UniProt Comments for PP32

Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Research Articles on PP32

1. our study reveals that ANP32A dysregulation may be a critical factor contributing to acute megakaryoblastic leukemia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PP32 antibody

Reference Product	PubMed Publications
SET antibody	>17 publications with PP32 and SET
ELAVL1 antibody	>5 publications with PP32 and ELAVL1
MAP1B antibody	>1 publications with PP32 and MAP1B
ATXN1 antibody	>1 publications with PP32 and ATXN1

Pathways associated with anti-PP32 antibody

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
HuR Stabilizes MRNA Pathway antibodies	HuR Stabilizes MRNA Pathway Diagram
Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies	Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram

Diseases associated with anti-PP32 antibody

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>4 publications with PP32 and Cell Transformation, Neoplastic
Ataxia Antibodies	>4 publications with PP32 and Ataxia
Adenocarcinoma Antibodies	>2 publications with PP32 and Adenocarcinoma
Prostatic Diseases Antibodies	>2 publications with PP32 and Prostatic Diseases
Liver Diseases Antibodies	>2 publications with PP32 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with PP32 and Liver Neoplasms
Breast Neoplasms Antibodies	>2 publications with PP32 and Breast Neoplasms
Necrosis Antibodies	>2 publications with PP32 and Necrosis
Lung Diseases Antibodies	>1 publications with PP32 and Lung Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with PP32 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-PP32 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>19 publications with PP32 and Brain
Nerve Antibodies	>14 publications with PP32 and Nerve
Prostate Antibodies	>7 publications with PP32 and Prostate
Blood Antibodies	>5 publications with PP32 and Blood
Kidney Antibodies	>4 publications with PP32 and Kidney
Liver Antibodies	>3 publications with PP32 and Liver
Spleen Antibodies	>3 publications with PP32 and Spleen
Ovary Antibodies	>3 publications with PP32 and Ovary
Pituitary Gland Antibodies	>2 publications with PP32 and Pituitary Gland
Pancreas Antibodies	>2 publications with PP32 and Pancreas