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PRDX3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS435087

This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22… More details

$435 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRDX3, Monoclonal Antibody
Full Product Name
PRDX3 Mouse mAb
Product Gene Name
anti-PRDX3 antibody
Product Synonym Names
anti-oxidant protein 1; antioxidant protein; Antioxidant protein 1; AOP-1; HBC189; mitochondrial thioredoxin dependent peroxide reductase; mitochondrial Trx dependent peroxide reductase; Perioredoxin-3; Peroxiredoxin III; Peroxiredoxin-3; Protein MER5; Protein MER5 homolog; PRX III; PRX-3; Prx-III; Prx3; Thioredoxin-dependent peroxide reductase, mitochondrial; AOP-1; AOP1; AW822249; D0Tohi1; Ef2l; HBC189; MER5; PRDX3; PRO1748; prx-III; Prx3; SP-22; SP22; TDXM
Clonality
Monoclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Preparation and Storage
Store at -20 degree C. Stable for one year from the date of shipment.
Molecular Weight
Predicted MW: 27kDa
3D Structure
ModBase 3D Structure for P30048
Source Note
This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human PRDX3

Product Categories/Family for anti-PRDX3 antibody

Cell Marker; Subcellular Marker; Membrane
Applications Tested/Suitable for anti-PRDX3 antibody
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-PRDX3 antibody
WB: 1:1000-1:5000
IP: 10 tests
FC/FACS: 1:100-1:200

Western Blot (WB) of anti-PRDX3 antibody

Mouse Anti-PRDX3 Monoclonal Antibody – Cat# MBS435087

Immunoprecipitation (IP) of anti-PRDX3 antibody

PRDX3 was immunoprecipitated from 1mg of Jurkat cells membrane fraction, blotted with M25079 of 10 ug. Western blot was performed from the immunopre-cipitate using M25079 at 1/1000 dilution. Anti-Mouse-IgG(HRP), specific to the non-reduced form of IgG, was used as secondary antibody at 1/10000 dilution. Lane 1: Jurkat cells membrane fraction. Lane2: IP product of Jurkat cells membrane fraction.

Predicted band size : 27 KDa
Observed band size : 27 KDa

Blocking and dilution buffer and concentration:5% milk/TBST.
Mouse Anti-PRDX3 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS435087

Flow Cytometry (FC/FACS) of anti-PRDX3 antibody

Flow cytometric analysis of 2% paraformaldehyde-fixed Jurkat (Human T cell leukemia cells from peripheral blood) cells labeling PRDX3 with M25079 at 1/200 dilution (red) compared with a mouse monoclonal IgG isotype control (blue) and an unlabelled control (cells without incubation with primary antibody, green). Goat anti-mouse IgG (FITC) at 1/300 dilution was used as the secondary antibody.
Mouse Anti-PRDX3 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS435087

Other Notes

Small volumes of anti-PRDX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRDX3 purchase

MBS435087 is an antibody targeting PRDX3. Also known as PRDX3 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PRDX3. It may not necessarily be applicable to this product.

NCBI GI #
695917253
NCBI GeneID
10935
NCBI Accession #
NP_001289201.1
UniProt Primary Accession #
P30048
UniProt Secondary Accession #
P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4; B2R7Z0; D3DRC9; E9PH29
UniProt Related Accession #
P30048
GenBank Nucleotide #
NM_001302272.1
NCBI Official Full Name
thioredoxin-dependent peroxide reductase, mitochondrial isoform c
NCBI Official Synonym Full Names
peroxiredoxin 3
NCBI Official Symbol
PRDX3
NCBI Official Synonym Symbols
AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
UniProt Protein Name
Thioredoxin-dependent peroxide reductase, mitochondrial
UniProt Synonym Protein Names
Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog
Protein Family
Thioredoxin-dependent peroxide reductase
UniProt Gene Name
PRDX3
UniProt Synonym Gene Names
AOP1; AOP-1; Prx-III
NCBI Protein Information
thioredoxin-dependent peroxide reductase, mitochondrial

UniProt Comments for PRDX3

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:7733872, PubMed:17707404). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:12492477).
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Research Articles on PRDX3

1. results suggest that decreased PRDX3 by excessive bile acids in trophoblasts plays a critical role in the pathogenesis and progression of Intrahepatic cholestasis of pregnancy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PRDX3 antibody

 Reference Product  PubMed Publications
 MYC antibody  >5 publications with PRDX3 and MYC
 MAX antibody  >3 publications with PRDX3 and MAX
 FANCG antibody  >2 publications with PRDX3 and FANCG
 IKBKB antibody  >1 publications with PRDX3 and IKBKB
 ATOX1 antibody  >1 publications with PRDX3 and ATOX1
 ABRA antibody  >1 publications with PRDX3 and ABRA
 RPS6KC1 antibody  >1 publications with PRDX3 and RPS6KC1

Pathways associated with anti-PRDX3 antibody

 Products by Pathway  Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies  Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram

Diseases associated with anti-PRDX3 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >12 publications with PRDX3 and Necrosis
 Liver Diseases Antibodies  >11 publications with PRDX3 and Liver Diseases
 Inflammation Antibodies  >9 publications with PRDX3 and Inflammation
 Nervous System Diseases Antibodies  >9 publications with PRDX3 and Nervous System Diseases
 Brain Diseases Antibodies  >9 publications with PRDX3 and Brain Diseases
 Cardiovascular Diseases Antibodies  >8 publications with PRDX3 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >7 publications with PRDX3 and Disease Models, Animal
 Liver Neoplasms Antibodies  >7 publications with PRDX3 and Liver Neoplasms
 Disease Progression Antibodies  >7 publications with PRDX3 and Disease Progression
 Carcinoma, Hepatocellular Antibodies  >5 publications with PRDX3 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-PRDX3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with PRDX3 and Blood
 Brain Antibodies  >17 publications with PRDX3 and Brain
 Liver Antibodies  >16 publications with PRDX3 and Liver
 Heart Antibodies  >11 publications with PRDX3 and Heart
 Lung Antibodies  >9 publications with PRDX3 and Lung
 Muscle Antibodies  >8 publications with PRDX3 and Muscle
 Vascular Antibodies  >8 publications with PRDX3 and Vascular
 Prostate Antibodies  >6 publications with PRDX3 and Prostate
 Nerve Antibodies  >6 publications with PRDX3 and Nerve
 Bone Antibodies  >6 publications with PRDX3 and Bone
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