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SAPAP1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9525087

MBS9525087 is an antibody targeting SAPAP1. Also known as SAPAP1 Monoclonal Antibody. Reactive in Human. Host: Mouse. More details

$300 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAPAP1, Monoclonal Antibody
Full Product Name
SAPAP1 Monoclonal Antibody
Product Gene Name
Product Synonym Names
Disks large-associated protein 1; DLGAP1; DAP1; GKAP; Disks large-associated protein 1; DAP-1; Guanylate kinase-associated protein; hGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1
Clonality
Monoclonal
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purity/Purification
Affinity purification
Specificity
SAPAP1 Monoclonal Antibody detects endogenous levels of SAPAP1 protein.
Preparation and Storage
Store at -20 degree C/1 year
Molecular Weight
108,873 Da
Chromosome Location
Chromosome: 18; NC_000018.9 (3496030..4455266, complement). Location: 18p11.31
OMIM
605445
3D Structure
ModBase 3D Structure for O14490
Immunogen
Purified recombinant fragment of human SAPAP1 expressed in E coli.
Modification
Unmodified/Total
Function
Part of the postsynaptic scaffold in neuronal cells.
Belongs to the SAPAP family.
Subcellular Location
Found in postsynaptic density of neuronal cells.
Subunit
Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.
Tissue Specificity
Expressed in brain.

Product Categories/Family for anti-SAPAP1 antibody

Applications Tested/Suitable for anti-SAPAP1 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
Application Notes for anti-SAPAP1 antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-SAPAP1 antibody

Western Blot analysis using SAPAP1 Monoclonal Antibody against HEK293 (1) and GKAP-hIgGFc transfected HEK293 (2) cell lysate.
Mouse Anti-SAPAP1 Monoclonal Antibody – Cat# MBS9525087

Immunohistochemistry (IHC) of anti-SAPAP1 antibody

Immunohistochemistry analysis of paraffin-embedded human liver cancer tissues with DAB staining using SAPAP1 Monoclonal Antibody.
Mouse Anti-SAPAP1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9525087

Immunofluorescence (IF) of anti-SAPAP1 antibody

Immunofluorescence analysis of NIH/3T3 cells using SAPAP1 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Mouse Anti-SAPAP1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS9525087

Testing Data of anti-SAPAP1 antibody

Mouse Anti-SAPAP1 Monoclonal Antibody, Testing Data – Cat# MBS9525087

Other Notes

Small volumes of anti-SAPAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SAPAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
disks large-associated protein 1 isoform 2
NCBI Official Synonym Full Names
discs, large (Drosophila) homolog-associated protein 1
NCBI Official Symbol
DLGAP1
NCBI Official Synonym Symbols
GKAP; DAP-1; hGKAP; SAPAP1; DAP-1-BETA; DAP-1-ALPHA
UniProt Protein Name
Disks large-associated protein 1
UniProt Synonym Protein Names
Guanylate kinase-associated protein; hGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1
UniProt Gene Name
DLGAP1
UniProt Synonym Gene Names
DAP1; GKAP; DAP-1; hGKAP; SAPAP1
UniProt Entry Name
DLGP1_HUMAN
NCBI Protein Information
disks large-associated protein 1; PSD-95/SAP90 binding protein 1; SAP90/PSD-95-associated protein 1; guanylate kinase-associated protein

UniProt Comments for SAPAP1

SAPAP1: Part of the postsynaptic scaffold in neuronal cells. Belongs to the SAPAP family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 18p11.31

Cellular Component: postsynaptic membrane; cell junction

Molecular Function: protein binding

Biological Process: synaptic transmission
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SAPAP1 antibody

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