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SSH1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6144594

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to… More details

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Product Overview

Online Datasheet in PDF
Product Name
SSH1, Monoclonal Antibody
Full Product Name
SSH1 (Protein Phosphatase Slingshot Homolog 1, SSH-like Protein 1, SSH1L, SSH-1L, hSSH-1L, KIAA1298) (Biotin)
Product Gene Name
Product Synonym Names
EC=3.1.3.16; EC=3.1.3.48
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2F9
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human SSH1.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
115,511 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (109176466..109251359, complement). Location: 12q24.11
OMIM
AB072355 mRNA
3D Structure
ModBase 3D Structure for Q8WYL5
Immunogen
Partial recombinant corresponding to aa752-850 from human SSH1 (NP_061857) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
PKSLLLKNSHCDKNPPSTEVVIKEESSPKKDMKPAKDLRLLFSNESEKPTTNSYLMQHQESIIQLQKAGLVRKHTKELERLKSVPADPAPPSRDGPAS
Conjugate
Biotin
Applications Tested/Suitable for anti-SSH1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-SSH1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SSH1 antibody

Western Blot detection against Immunogen (36.89kD).
Mouse Anti-SSH1 Monoclonal Antibody – Cat# MBS6144594

Western Blot (WB) of anti-SSH1 antibody

Western Blot analysis of SSH1 expression in transfected 293T cell line by SSH1 monoclonal antibody. Lane 1: SSH1 transfected lysate (115.5kD). Lane 2: Non-transfected lysate.
Mouse Anti-SSH1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6144594

Other Notes

Small volumes of anti-SSH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSH1 purchase

MBS6144594 is an antibody targeting SSH1. Also known as SSH1 (Protein Phosphatase Slingshot Homolog 1, SSH-like Protein 1, SSH1L, SSH-1L, hSSH-1L, KIAA1298) (Biotin). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SSH1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase Slingshot homolog 1 isoform 1
NCBI Official Synonym Full Names
slingshot protein phosphatase 1
NCBI Official Symbol
SSH1
NCBI Official Synonym Symbols
SSH1L
UniProt Protein Name
Protein phosphatase Slingshot homolog 1
UniProt Synonym Protein Names
SSH-like protein 1; SSH-1L; hSSH-1L
UniProt Gene Name
SSH1
UniProt Synonym Gene Names
KIAA1298; SSH1L; SSH-1L; hSSH-1L
NCBI Protein Information
protein phosphatase Slingshot homolog 1; hSSH-1L; SSH-like protein 1; slingshot homolog 1

UniProt Comments for SSH1

Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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