Mouse Anti-SUMO3 Monoclonal Antibody – Cat# MBS631463

Western blot analysis of anti-Beta-actin Monoclonal Antibody in HL-60 cell line lysates (37ug/lane). Beta-actin (arrow) was detected using the purified Mab.

SUMO3 Antibody – Mouse Monoclonal

Name: SUMO3 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS631463
Price: 865 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS631463

$865 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SUMO3, Monoclonal Antibody

Full Product Name

SUMO3 (Small Ubiquitin-Related Modifier 3, SUMO-3, Ubiquitin-Like Protein SMT3A, SMT3 Homolog 1, SUMO-2, SMT3A, SMT3H1)

Product Gene Name

anti-SUMO3 antibody

Product Synonym Names

Anti -SUMO3 (Small Ubiquitin-Related Modifier 3, SUMO-3, Ubiquitin-Like Protein SMT3A, SMT3 Homolog 1, SUMO-2, SMT3A, SMT3H1)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

10i72

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human SUMO3.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

11,637 Da

Chromosome Location

Chromosome: 21; NC_000021.8 (46225532..46238044, complement). Location: 21q22.3

OMIM

602231

3D Structure

ModBase 3D Structure for P55854

Immunogen

Purified recombinant GST-SUMO3 fusion protein.

Product Categories/Family for anti-SUMO3 antibody

Antibodies; Abs to Ubiquitin

Applications Tested/Suitable for anti-SUMO3 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-SUMO3 antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1000
Western Blot: 1:100-1:500

Other Notes

Small volumes of anti-SUMO3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SUMO3 purchase

MBS631463 is an antibody targeting SUMO3. Also known as SUMO3 (Small Ubiquitin-Related Modifier 3, SUMO-3, Ubiquitin-Like Protein SMT3A, SMT3 Homolog 1, SUMO-2, SMT3A, SMT3H1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SUMO3. It may not necessarily be applicable to this product.

NCBI GI #

48928058

NCBI GeneID

6612

NCBI Accession #

NP_008867.2

UniProt Primary Accession #

P55854

UniProt Secondary Accession #

Q53HI9; Q6FGD4; Q9BWR4; B2R5X4

UniProt Related Accession #

P55854

GenBank Nucleotide #

NM_006936.2

NCBI Official Full Name

small ubiquitin-related modifier 3

NCBI Official Synonym Full Names

SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)

NCBI Official Symbol

SUMO3

NCBI Official Synonym Symbols

SMT3A; Smt3B; SMT3H1; SUMO-3

UniProt Protein Name

Small ubiquitin-related modifier 3

UniProt Synonym Protein Names

SMT3 homolog 1; SUMO-2; Ubiquitin-like protein SMT3B

Protein Family

Small ubiquitin-related modifier

UniProt Gene Name

SUMO3

UniProt Synonym Gene Names

SMT3B; SMT3H1

UniProt Entry Name

SUMO3_HUMAN

NCBI Protein Information

small ubiquitin-related modifier 3; SUMO-2; SMT3 homolog 1; OTTHUMP00000115275; OTTHUMP00000115276; OTTHUMP00000115277; ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; SMT3 suppressor of mif two 3 homolog 1

NCBI Summary for SUMO3

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM]

UniProt Comments for SUMO3

SUMO3: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Covalently attached to a number of proteins. Interacts with USP25 (via ts SIM domain); the interaction sumoylates USP25 and inhibits its ubiquitin hydrolyzing activity. Interacts with SAE2 and UBE2I. Expressed predominantly in liver. Belongs to the ubiquitin family. SUMO subfamily.

Protein type: Ubiquitin-like modifier

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: nucleoplasm; kinetochore; PML body; cytoplasm; nucleus

Molecular Function: protein binding; SUMO ligase activity

Biological Process: protein sumoylation; cellular protein metabolic process; post-translational protein modification

Research Articles on SUMO3

1. SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SUMO3 antibody

Reference Product	PubMed Publications
RANGAP1 antibody	>7 publications with SUMO3 and RANGAP1
PML antibody	>7 publications with SUMO3 and PML
SENP2 antibody	>5 publications with SUMO3 and SENP2
TDG antibody	>2 publications with SUMO3 and TDG
SAE1 antibody	>2 publications with SUMO3 and SAE1
PIAS4 antibody	>2 publications with SUMO3 and PIAS4

Pathways associated with anti-SUMO3 antibody

Products by Pathway	Pathway Diagram
Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies	Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram

Diseases associated with anti-SUMO3 antibody

Disease Name	Pubmed Publications
Abnormalities, Multiple Antibodies	>3 publications with SUMO3 and Abnormalities, Multiple
Liver Diseases Antibodies	>2 publications with SUMO3 and Liver Diseases
Inflammation Antibodies	>2 publications with SUMO3 and Inflammation
Neurodegenerative Diseases Antibodies	>2 publications with SUMO3 and Neurodegenerative Diseases
Leukemia, Myeloid, Acute Antibodies	>2 publications with SUMO3 and Leukemia, Myeloid, Acute
Adenocarcinoma Antibodies	>1 publications with SUMO3 and Adenocarcinoma
Colorectal Neoplasms Antibodies	>1 publications with SUMO3 and Colorectal Neoplasms
Bone Diseases, Developmental Antibodies	>1 publications with SUMO3 and Bone Diseases, Developmental
Colonic Neoplasms Antibodies	>1 publications with SUMO3 and Colonic Neoplasms
Stroke Antibodies	>1 publications with SUMO3 and Stroke

Organs/Tissues associated with anti-SUMO3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with SUMO3 and Blood
Brain Antibodies	>5 publications with SUMO3 and Brain
Kidney Antibodies	>3 publications with SUMO3 and Kidney
Liver Antibodies	>3 publications with SUMO3 and Liver
Testis Antibodies	>3 publications with SUMO3 and Testis
Embryonic Tissue Antibodies	>2 publications with SUMO3 and Embryonic Tissue
Nerve Antibodies	>1 publications with SUMO3 and Nerve
Placenta Antibodies	>1 publications with SUMO3 and Placenta
Skin Antibodies	>1 publications with SUMO3 and Skin
Mouth Antibodies	>1 publications with SUMO3 and Mouth