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AVEN Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6210367

MBS6210367 is an antibody targeting AVEN. Also known as AVEN (Cell Death Regulator Aven, PDCD12) (MaxLight 550). Reactive in Human, Mouse, Rat. Host: Mouse. AVEN protects against apoptosis mediated by Apaf-1. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AVEN, Monoclonal Antibody
Full Product Name
AVEN (Cell Death Regulator Aven, PDCD12) (MaxLight 550)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
2B10
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human AVEN. Species Crossreactivity: mouse and rat.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
38,506 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (34158428..34331303, complement). Location: 15q13.1
OMIM
605265
3D Structure
ModBase 3D Structure for Q9NQS1
Immunogen
Partial recombinant corresponding to aa71-171 from human AVEN (NP_065104) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
APRGSRREPGGWGAGASAPVEDDSDAETYGEENDEQGNYSKRKIVSNWDRYQDIEKEVNNESGESQRGTDFSVLLSSAGDSFSQFRFAEEKEWDSEASCP
Conjugate
MaxLight550

Product Categories/Family for anti-AVEN antibody

Applications Tested/Suitable for anti-AVEN antibody
FLISA, Western Blot (WB)
Application Notes for anti-AVEN antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-AVEN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AVEN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cell death regulator Aven
NCBI Official Synonym Full Names
apoptosis, caspase activation inhibitor
NCBI Official Symbol
AVEN
NCBI Official Synonym Symbols
PDCD12
UniProt Protein Name
Cell death regulator Aven
Protein Family
UniProt Gene Name
AVEN
UniProt Entry Name
AVEN_HUMAN
NCBI Protein Information
cell death regulator Aven; programmed cell death 12

UniProt Comments for AVEN

AVEN: Protects against apoptosis mediated by Apaf-1. Binds Apaf-1, BCL-2 and BAD (Bcl-xl). Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.

Protein type: Inhibitor; Apoptosis

Chromosomal Location of Human Ortholog: 15q13.1

Cellular Component: membrane; endomembrane system; intracellular

Molecular Function: protein binding

Biological Process: apoptosis; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AVEN antibody

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