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CD3 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2568295

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3epsilon, delta, gamma and zeta chains. It forms a TCR complex… More details

$160 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD3, Monoclonal Antibody
Full Product Name
EV450 Anti-Mouse CD3 Antibody [17A2]
Product Gene Name
Product Synonym Names
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain; CD3E/D/G/Z; CD3e/d/g/z; CD3E/D/G/Z; CD3
Clonality
Monoclonal
Isotype
Rat IgG2b, kappa
Clone Number
17A2
Host
Rat
Species Reactivity
Mouse
Form/Format
PBS with 0.05% Proclin300, 1% BSA
Concentration
0.2mg/mL (lot specific)
Preparation and Storage
Store at 2~8 degree C and protected from prolonged exposure to light. Do not freeze.
Matching Pairs
Molecular Weight
19,032 Da
3D Structure
ModBase 3D Structure for P04235
Conjugation
EV450

Product Categories/Family for anti-CD3 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD3 antibody
Flow Cytometry (FC/FACS/FCM)

Flow Cytometry (FC/FACS) of anti-CD3 antibody

Mouse splenocytes are stained with EV450 Anti-Mouse CD3 Antibody[Used at 0.02 ?g/106 cells dilution](filled gray histogram). Unstained splenocytes(blank black histogram) are used as control.
Rat Anti-CD3 Monoclonal Antibody – Cat# MBS2568295

Other Notes

Small volumes of anti-CD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD3 purchase

MBS2568295 is an antibody targeting CD3. Also known as EV450 Anti-Mouse CD3 Antibody [17A2]. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
T-cell surface glycoprotein CD3 delta chain
NCBI Official Synonym Full Names
CD3 antigen, delta polypeptide
NCBI Official Symbol
Cd3d
NCBI Official Synonym Symbols
T3d
UniProt Protein Name
T-cell surface glycoprotein CD3 delta chain
UniProt Synonym Protein Names
T-cell receptor T3 delta chain; CD_antigen: CD3d
Protein Family
UniProt Gene Name
Cd3d
UniProt Synonym Gene Names
T3d
UniProt Entry Name
CD3D_MOUSE
NCBI Protein Information
T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain

UniProt Comments for CD3

CD3D: a T cell surface glycoprotein that is a component of the T cell antigen receptor. A defect in this protein causes a severe combined immunodeficiency characterized by the absence of T cells but normal B cells. Contains 1 ITAM domain.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: T cell receptor complex; membrane; integral to membrane; alpha-beta T cell receptor complex

Molecular Function: protein binding; transmembrane receptor activity; protein heterodimerization activity

Biological Process: cell surface receptor linked signal transduction; T cell activation; protein complex assembly; positive thymic T cell selection
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD3 antibody

 Reference Product  PubMed Publications
 Cd3e antibody  >11 publications with CD3 and Cd3e
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