CD2 Antibody – Rat Monoclonal

CD2: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.

Protein type: Cell surface; Apoptosis; Membrane protein, integral

Cellular Component: internal side of plasma membrane; anchored to plasma membrane; protein complex; cell surface; membrane; integral to membrane; extracellular region; intercellular junction; lipid raft; external side of plasma membrane

Molecular Function: protein binding; protein homodimerization activity; protein self-association; receptor activity; receptor tyrosine kinase binding; glycoprotein binding; antigen binding; protein kinase binding; receptor binding

Biological Process: heterotypic cell-cell adhesion; cell-cell adhesion; T cell activation; positive regulation of tumor necrosis factor production; cell adhesion