• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IL-12p40 Mouse Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692489

IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities,… More details

$305 / 0.002 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-12p40, Active Protein
Full Product Name
Mouse IL-12p40
Product Gene Name
Product Synonym Names
Interleukin-12; NKSF; CTL Maturation Factor (TCMF); Cytotoxic Lymphocyte Maturation Factor (CLMF);TSF;; p40:Interleukin-12 subunit beta; IL-12 subunit p40; IL-12B; Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit(CLMF p40); NK cell Stimulating Factor Chain 2
Sequence
MWELEKDVYV VEVDWTPDAP GETVNLTCDT PEEDDITWTS DQRHGV IGSG KTLTITVKEF LDAGQYTCHK GGETLSHSHL LLHKKENGIW S TEILKNFKN KTFLKCEAPN YSGRFTCSWL VQRNMDLKFN IKSSSSS PDS RAVTCGMASL SAEKVTLDQR DYEKYSVSCQ EDVTCPTAEE TL PIELALEA RQQNKYENYS TSFFIRDIIK PDPPKNLQMK PLKNSQVE VS WEYPDSWSTP HSYFSLKFFV RIQRKKEKMK ETEEGCNQKG AFL VEKTSTE VQCKGGNVCV QAQDRYYNSS CSKWACVPCR VRS
Host
HEK 293 cells
Species Reactivity
Mouse
Form/Format
Lyophilized
Purity/Purification
> 95% by SDS-PAGE & HPLC analyses
Molecular Weight
38,235 Da
3D Structure
ModBase 3D Structure for P43432
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Determined by its ability to inhibit the proliferative effect of 2 ng/ml mIL-12p70 in T-cell enriched PBMCs.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of IL-12p40 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-12p40 purchase

MBS692489 is an active protein targeting IL-12p40. Also known as Mouse IL-12p40. Reactive in Mouse. Host: HEK 293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-12p40. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-12 subunit beta
NCBI Official Synonym Full Names
interleukin 12b
NCBI Official Symbol
Il12b
NCBI Official Synonym Symbols
p40; Il-12b; Il12p40; Il-12p40
UniProt Protein Name
Interleukin-12 subunit beta
UniProt Synonym Protein Names
Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40
UniProt Gene Name
Il12b
UniProt Synonym Gene Names
IL-12B; CLMF p40
NCBI Protein Information
interleukin-12 subunit beta

NCBI Summary for IL-12p40

This gene encodes the beta subunit p40 of the Interleukin 12 (IL-12) family of cytokines. Members of the IL-12 family form heterodimers consisting of heavy and light subunits linked by disulfide bonds. The product of this gene, p40, is a subunit of interleukins IL-12 and IL-23. [provided by RefSeq, Dec 2014]
Show more

UniProt Comments for IL-12p40

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000