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CD185 Antibody – Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2585273

MBS2585273 is an antibody targeting CD185. Also known as Purified Anti-Mouse CD185 Antibody [L138D7]. Reactive in Mouse. Host: Rat. More details

$150 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD185, Antibody
Full Product Name
Purified Anti-Mouse CD185 Antibody [L138D7]
Product Gene Name
anti-CD185 antibody
Product Synonym Names
Blr; Gpcr; CXCR; Blr1; Gpcr6; Cxcr5; BLR1
Isotype
IgG2b, kappa
Clone Number
L138D7
Host
Rat
Species Reactivity
Mouse
Preparation and Storage
Store at 4 degree C valid for 12 months or -20 degree C valid for long term storage, avoid freeze/thaw cycles.
Molecular Weight
42,115 Da
3D Structure
ModBase 3D Structure for Q04683
Conjugation
Unconjugated

Product Categories/Family for anti-CD185 antibody

Antibodies and Reagents; Primary Antibodies; Flow Cytometry Antibodies
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD185 antibody
Flow Cytometry (FC/FACS)

Testing Data of anti-CD185 antibody

C57/BL6 Mouse splenocytes were stained with 0.2 μg Purified Anti-Mouse CD185 Antibody[L138D7](Right) and 0.2 μg Rat IgG2b, κ Isotype Control (Left), followed by APC-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse B220 FITC-conjugated Monoclonal Antibody.
Rat Anti-CD185 Antibody – Cat# MBS2585273

Other Notes

Small volumes of anti-CD185 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD185. It may not necessarily be applicable to this product.

NCBI GI #
42475950
NCBI GeneID
12145
NCBI Accession #
NP_031577.2
UniProt Primary Accession #
Q04683
UniProt Secondary Accession #
Q6P3C2
UniProt Related Accession #
Q04683
GenBank Nucleotide #
NM_007551.2
NCBI Official Full Name
C-X-C chemokine receptor type 5
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 5
NCBI Official Symbol
Cxcr5
NCBI Official Synonym Symbols
Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5
UniProt Protein Name
C-X-C chemokine receptor type 5
UniProt Synonym Protein Names
Burkitt lymphoma receptor 1 homolog; CD_antigen: CD185
Protein Family
C-X-C chemokine receptor
UniProt Gene Name
Cxcr5
UniProt Synonym Gene Names
Blr1; Gpcr6; CXC-R5; CXCR-5
UniProt Entry Name
CXCR5_MOUSE
NCBI Protein Information
C-X-C chemokine receptor type 5

UniProt Comments for CD185

CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Cellular Component: membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; signal transducer activity; chemokine receptor activity; C-X-C chemokine receptor activity

Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; B cell activation; immune response; signal transduction; chemotaxis; lymph node development
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Research Articles on CD185

1. Results identify p66Shc as a negative regulator of B-cell chemotaxis and suggest a role for this adaptor in the control of B-cell homing via CXCR4/5.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD185 antibody

 Reference Product  PubMed Publications
 Cxcl13 antibody  >201 publications with CD185 and Cxcl13
 Ccr7 antibody  >147 publications with CD185 and Ccr7
 Ccr6 antibody  >71 publications with CD185 and Ccr6
 Cxcl10 antibody  >28 publications with CD185 and Cxcl10
 Ccl5 antibody  >15 publications with CD185 and Ccl5
 Cxcl9 antibody  >6 publications with CD185 and Cxcl9

Pathways associated with anti-CD185 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram

Diseases associated with anti-CD185 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >93 publications with CD185 and Inflammation
 Necrosis Antibodies  >42 publications with CD185 and Necrosis
 Disease Models, Animal Antibodies  >37 publications with CD185 and Disease Models, Animal
 Kidney Diseases Antibodies  >21 publications with CD185 and Kidney Diseases
 Carcinoma Antibodies  >20 publications with CD185 and Carcinoma
 Liver Diseases Antibodies  >19 publications with CD185 and Liver Diseases
 Lung Diseases Antibodies  >19 publications with CD185 and Lung Diseases
 Neoplasms, Experimental Antibodies  >17 publications with CD185 and Neoplasms, Experimental
 Skin Diseases Antibodies  >17 publications with CD185 and Skin Diseases
 Prostatic Neoplasms Antibodies  >8 publications with CD185 and Prostatic Neoplasms
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