Ilf3 Peptide - C-Terminal Region Blocking Peptide

The protein encoded by this gene contains two double-stranded RNA binding domains and functions in the post-transcriptional regulation of gene expression. It is a component of an RNA-protein complex that may be involved in mediating the export of messenger RNAs. Alternative splicing results in multiple transcript variants encoding distinct isoforms. These isoforms are grouped into two categories, NFAR-1 or NFAR-2, based on variation at the C-terminus. [provided by RefSeq, Mar 2013]

NFAT90: a double-stranded RNA (dsRNA)-binding protein implicated in the regulation of gene expression . Phosphorylated in a double-stranded RNA-dependent manner possibly by PKR. Five different splice-variant isoforms have been described.

Protein type: RNA-binding; Nucleolus; Transcription factor; DNA-binding

Cellular Component: nucleoplasm; membrane; mitochondrion; cytoplasm; nucleolus; ribonucleoprotein complex; nucleus

Molecular Function: enzyme binding; DNA binding; RNA binding; double-stranded RNA binding

Biological Process: negative regulation of viral genome replication; protein amino acid methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of translation; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; defense response to virus; protein amino acid phosphorylation