RECK Peptide - N-Terminal Region Blocking Peptide

Name: RECK Peptide - N-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3248494
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3248494

This is a synthetic peptide designed for use in combination with anti- RECK Antibody, madeTarget Description: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RECK, Blocking Peptide

Full Product Name

RECK Peptide - N-terminal region

Product Gene Name

RECK blocking peptide

Product Synonym Gene Name

St15; mRECK

Sequence

Synthetic peptide located within the following region: MNSSLPGVFK KSDGWVGLGC CELAIGLECR QACKQASSKN DISKVCRKEY

Species Reactivity

Mouse

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

RECK peptide (MBS3248494) is used for blocking the activity of RECK antibody (MBS3224158)

Molecular Weight

106 kDa

Product Categories/Family for RECK blocking peptide

Peptide

Other Notes

Small volumes of RECK blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RECK purchase

MBS3248494 is a blocking peptide targeting RECK. Also known as RECK Peptide - N-terminal region. Reactive in Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RECK. It may not necessarily be applicable to this product.

NCBI GI #

172072643

NCBI GeneID

53614

NCBI Accession #

NP_057887.2

UniProt Primary Accession #

Q9Z0J1

UniProt Related Accession #

Q9Z0J1

GenBank Nucleotide #

NM_016678.2

NCBI Official Full Name

reversion-inducing cysteine-rich protein with Kazal motifs

NCBI Official Synonym Full Names

reversion-inducing-cysteine-rich protein with kazal motifs

NCBI Official Symbol

Reck

NCBI Official Synonym Symbols

St15; mRECK

UniProt Protein Name

Reversion-inducing cysteine-rich protein with Kazal motifs

Protein Family

Reversion-inducing cysteine-rich protein

UniProt Gene Name

Reck

UniProt Synonym Gene Names

mRECK

UniProt Entry Name

RECK_MOUSE

NCBI Protein Information

reversion-inducing cysteine-rich protein with Kazal motifs

UniProt Comments for RECK

RECK: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. Interacts with MMP-9. Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.

Protein type: Tumor suppressor; Membrane protein, GPI anchor

Cellular Component: membrane; plasma membrane

Molecular Function: endopeptidase inhibitor activity; metalloendopeptidase inhibitor activity; protease inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: blood vessel maturation; embryo implantation; embryonic forelimb morphogenesis; extracellular matrix organization and biogenesis; negative regulation of cell migration; negative regulation of peptidase activity; positive regulation of Notch signaling pathway

Research Articles on RECK

1. Reck was identified to be one of the target genes of miR-497-5p, and Reck could suppress the expression of matrix metalloproteinase-2 (Mmp2) and Mmp9, which could activate latent transforming growth factor-beta1 (TGF-beta1).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RECK blocking peptide

Reference Product	PubMed Publications
Mmp9 blocking peptide	>24 publications with RECK and Mmp9
Mmp2 blocking peptide	>20 publications with RECK and Mmp2
Mmp14 blocking peptide	>10 publications with RECK and Mmp14
Timp2 blocking peptide	>8 publications with RECK and Timp2
Erbb2 blocking peptide	>4 publications with RECK and Erbb2
Vegfa blocking peptide	>3 publications with RECK and Vegfa

Pathways associated with RECK blocking peptide

Products by Pathway	Pathway Diagram
MicroRNAs In Cancer Pathway antibodies	MicroRNAs In Cancer Pathway Diagram
MicroRNAs In Cancer Pathway antibodies	MicroRNAs In Cancer Pathway Diagram

Diseases associated with RECK blocking peptide

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>189 publications with RECK and Lung Neoplasms
Carcinoma, Non-Small-Cell Lung Antibodies	>148 publications with RECK and Carcinoma, Non-Small-Cell Lung
Neoplasm Metastasis Antibodies	>95 publications with RECK and Neoplasm Metastasis
Nervous System Diseases Antibodies	>86 publications with RECK and Nervous System Diseases
Neoplasm Invasiveness Antibodies	>78 publications with RECK and Neoplasm Invasiveness
Adenocarcinoma Antibodies	>73 publications with RECK and Adenocarcinoma
Brain Diseases Antibodies	>40 publications with RECK and Brain Diseases
Breast Neoplasms Antibodies	>31 publications with RECK and Breast Neoplasms
Neoplasms, Experimental Antibodies	>30 publications with RECK and Neoplasms, Experimental
Liver Diseases Antibodies	>30 publications with RECK and Liver Diseases

Organs/Tissues associated with RECK blocking peptide

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>220 publications with RECK and Lung
Brain Antibodies	>59 publications with RECK and Brain
Skin Antibodies	>37 publications with RECK and Skin
Eye Antibodies	>31 publications with RECK and Eye
Lymph Node Antibodies	>29 publications with RECK and Lymph Node
Connective Tissue Antibodies	>24 publications with RECK and Connective Tissue
Embryonic Tissue Antibodies	>18 publications with RECK and Embryonic Tissue
Pancreas Antibodies	>9 publications with RECK and Pancreas
Thyroid Antibodies	>4 publications with RECK and Thyroid
Inner Ear Antibodies	>1 publications with RECK and Inner Ear