Complement Factor D (CFD) ELISA Kit for Mouse

Name: Mouse CFD ELISA Kit; Complement Factor D; MyBioSource
Brand: MyBioSource
SKU: MBS2087907
Price: 575 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2087907

MBS2087907 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement Factor D (CFD) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$575 / 24-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Complement Factor D (CFD), ELISA Kit

Full Product Name

Mouse Complement Factor D (CFD) Mini Samples ELISA Kit

Product Gene Name

CFD elisa kit

Product Synonym Names

CF-D; DF; PFD; ADN; Adipsin; Properdin Factor D; C3 convertase activator

Species Reactivity

Mouse

Assay Type

Double-antibody Sandwich ELISA for Antigen Detection

Samples

Serum, plasma, Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Detection Range

0.47-30ng/mL

Sensitivity

0.22ng/mL

Molecular Weight

27,986 Da

3D Structure

ModBase 3D Structure for P03953

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Product Categories/Family for CFD elisa kit

Immune molecule

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of CFD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CFD. It may not necessarily be applicable to this product.

NCBI GI #

632794820

NCBI GeneID

11537

NCBI Accession #

NP_001278844.1

UniProt Primary Accession #

P03953

UniProt Secondary Accession #

Q61280

UniProt Related Accession #

P03953

GenBank Nucleotide #

NM_001291915.2

NCBI Official Full Name

complement factor D isoform 2 preproprotein

NCBI Official Synonym Full Names

complement factor D (adipsin)

NCBI Official Symbol

Cfd

NCBI Official Synonym Symbols

DF; Adn

UniProt Protein Name

Complement factor D

UniProt Synonym Protein Names

28 kDa adipocyte protein; Adipsin; C3 convertase activator; Properdin factor D

Protein Family

Complement factor

UniProt Gene Name

Cfd

UniProt Synonym Gene Names

Adn; Df

NCBI Protein Information

complement factor D

NCBI Summary for CFD

This gene encodes a serine protease that plays an important role in the alternative pathway of complement activation for pathogen recognition and elimination. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that in turn cleaves factor B in the complement pathway. This gene is expressed in adipocytes and the mature enzyme is secreted into the bloodstream. Mice lacking the encoded product cannot initiate alternative pathway of complement activation. [provided by RefSeq, Jul 2016]

UniProt Comments for CFD

CFD: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Defects in CFD are the cause of complement factor D deficiency (CFDD). CFDD is an immunologic disorder characterized by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.46; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10 C1|10 39.72 cM

Cellular Component: extracellular space

Molecular Function: endopeptidase activity

Biological Process: Notch signaling pathway

Research Articles on CFD

1. An essential role for Factor D in the ability of the liver to recover from acute toxic injury, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CFD elisa kit

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Alternative Complement Activation Pathway antibodies	Alternative Complement Activation Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Initial Triggering Of Complement Pathway antibodies	Initial Triggering Of Complement Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with CFD elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>463 publications with CFD and Cardiovascular Diseases
Heart Diseases Antibodies	>134 publications with CFD and Heart Diseases
Hyperplasia Antibodies	>35 publications with CFD and Hyperplasia
Disease Models, Animal Antibodies	>23 publications with CFD and Disease Models, Animal
Carcinoma Antibodies	>22 publications with CFD and Carcinoma
Inflammation Antibodies	>20 publications with CFD and Inflammation
Hypertension Antibodies	>20 publications with CFD and Hypertension
Liver Diseases Antibodies	>14 publications with CFD and Liver Diseases
Kidney Diseases Antibodies	>10 publications with CFD and Kidney Diseases
Hypertrophy Antibodies	>9 publications with CFD and Hypertrophy

Organs/Tissues associated with CFD elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>829 publications with CFD and Blood
Other Antibodies	>314 publications with CFD and Other
Lung Antibodies	>124 publications with CFD and Lung
Muscle Antibodies	>35 publications with CFD and Muscle
Joint Antibodies	>31 publications with CFD and Joint
Eye Antibodies	>28 publications with CFD and Eye
Skin Antibodies	>27 publications with CFD and Skin
Kidney Antibodies	>13 publications with CFD and Kidney
Thyroid Antibodies	>11 publications with CFD and Thyroid
Embryonic Tissue Antibodies	>8 publications with CFD and Embryonic Tissue