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Ip-10 ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9502099

MBS9502099 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IP-10, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

$405 / 1 Kit +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IP-10, ELISA Kit
Full Product Name
IP-10 (Murine) OmniKine ELISA Kit
Product Gene Name
IP-10 elisa kit
Product Synonym Gene Name
CXCL10
Product Synonym Names
C-X-C Motif Chemokine Ligand 10; Small Inducible Cytokine Subfamily B (Cys-X-Cys); Member 10; 10 KDa Interferon Gamma-Induced Protein; Chemokine (C-X-C Motif) Ligand 10; Small-Inducible Cytokine B10; SCYB10; INP10; IP-10; Protein 10 From Interferon (Gamma)-Induced Cell Line; Interferon-Inducible Cytokine IP-10; C-X-C Motif Chemokine 10; Gamma IP10; GIP-10; IFI10; Crg- 2; Mob-1; C7
Species Reactivity
Mouse
Assay Type
Sandwich ELISA
Detection Range
32-2000 pg/ml
Form/Format
12 x 8-Well Microstrips
Specificity
The OmniKine Murine IP-10 ELISA is capable of recognizing both recombinant and naturally produced Murine IP-10 proteins. The antigens listed below were tested at 50 ng/ml the following antigens exhibited less than 2% cross reactivity
Rat IP-10
The antigens listed below were tested at 50ng/ml the following antigens did not exhibit significant cross reactivity
Human ENA-78, GCP-2. I-TAC, IL-8, IP-10, MIG, NAP-2, PF-4
Murine BCA-1/BLC, I-TAC, LIX, MIG, PF-4, SDF-1alpha, SDF-1beta
RAT GRO/KC
Preparation and Storage
Store entire kit at 4 degree C until use.
Molecular Weight
10,789 Da
3D Structure
ModBase 3D Structure for P17515
Detection Method
Colorimetric 450 nm
Subtype
None

Other Notes

Small volumes of IP-10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IP-10. It may not necessarily be applicable to this product.

NCBI GI #
10946576
NCBI GeneID
15945
NCBI Accession #
NP_067249.1
UniProt Primary Accession #
P17515
UniProt Related Accession #
P17515
GenBank Nucleotide #
NM_021274.2
NCBI Official Full Name
C-X-C motif chemokine 10
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol
Cxcl10
NCBI Official Synonym Symbols
C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
UniProt Protein Name
C-X-C motif chemokine 10
UniProt Synonym Protein Names
10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; C7; Interferon-gamma induced protein CRG-2; Small-inducible cytokine B10
UniProt Gene Name
Cxcl10
UniProt Synonym Gene Names
Crg2; Ifi10; Inp10; Scyb10; Gamma-IP10; IP-10
NCBI Protein Information
C-X-C motif chemokine 10

UniProt Comments for IP-10

CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5 E2|5 46.57 cM

Cellular Component: external side of plasma membrane; extracellular region; extracellular space

Molecular Function: chemokine activity; CXCR3 chemokine receptor binding; cytokine activity; heparin binding

Biological Process: chemotaxis; defense response; defense response to virus; endothelial cell activation; G-protein coupled receptor signaling pathway; immune response; inflammatory response; negative regulation of angiogenesis; negative regulation of myoblast differentiation; positive regulation of cAMP metabolic process; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of leukocyte chemotaxis; positive regulation of release of sequestered calcium ion into cytosol; regulation of cell proliferation; response to lipopolysaccharide
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Research Articles on IP-10

1. Collectively, these results suggest that the CXCL10/CXCR3-mediated NF-kappaB signaling pathway plays a role in the control of autonomous regulation of CXCL10 and malignant tumor properties in breast cancer 4T1 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IP-10 elisa kit

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram

Diseases associated with IP-10 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1158 publications with IP-10 and Inflammation
 Necrosis Antibodies  >669 publications with IP-10 and Necrosis
 Disease Models, Animal Antibodies  >337 publications with IP-10 and Disease Models, Animal
 Lung Diseases Antibodies  >332 publications with IP-10 and Lung Diseases
 Liver Diseases Antibodies  >229 publications with IP-10 and Liver Diseases
 Cardiovascular Diseases Antibodies  >169 publications with IP-10 and Cardiovascular Diseases
 Fibrosis Antibodies  >126 publications with IP-10 and Fibrosis
 Neoplasms, Experimental Antibodies  >113 publications with IP-10 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >86 publications with IP-10 and Kidney Diseases
 Lung Injury Antibodies  >63 publications with IP-10 and Lung Injury

Organs/Tissues associated with IP-10 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >159 publications with IP-10 and Lymph Node
 Spleen Antibodies  >129 publications with IP-10 and Spleen
 Bone Marrow Antibodies  >124 publications with IP-10 and Bone Marrow
 Eye Antibodies  >94 publications with IP-10 and Eye
 Intestine Antibodies  >90 publications with IP-10 and Intestine
 Embryonic Tissue Antibodies  >52 publications with IP-10 and Embryonic Tissue
 Thymus Antibodies  >52 publications with IP-10 and Thymus
 Mammary Gland Antibodies  >8 publications with IP-10 and Mammary Gland
 Epididymis Antibodies  >1 publications with IP-10 and Epididymis
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