Pkcz ELISA Kit for Mouse

PKCZ: an AGC kinase of the PKC family. An atypical PKC: its activity is not regulated by Ca2+, PS, DAG or phorbol esters. Constitutively active.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.13; Protein kinase, AGC; AGC group; PKC family; Iota subfamily

Cellular Component: tight junction; nuclear matrix; protein complex; apical cortex; intracellular membrane-bound organelle; leading edge; nuclear envelope; cell cortex; intercellular junction; cytosol; lipid raft; axon hillock; filamentous actin; perinuclear region of cytoplasm; apical plasma membrane; cytoplasm; plasma membrane; microtubule organizing center; cell junction; nucleus; endosome

Molecular Function: transferase activity; protein domain specific binding; protein serine/threonine kinase activity; protein binding; potassium channel regulator activity; protein kinase C activity; phospholipase binding; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase binding; ATP binding; protein kinase activity

Biological Process: protein heterooligomerization; membrane hyperpolarization; negative regulation of insulin receptor signaling pathway; signal transduction; protein amino acid phosphorylation; positive regulation of synaptic transmission; activation of NF-kappaB transcription factor; positive regulation of interleukin-4 production; positive regulation of glucose import; cell surface receptor linked signal transduction; positive regulation of T-helper 2 cell differentiation; negative regulation of hydrolase activity; positive regulation of cell proliferation; vesicle transport along microtubule; inflammatory response; positive regulation of cell-matrix adhesion; phospholipase D activation; negative regulation of peptidyl-tyrosine phosphorylation; cell migration; activation of protein kinase B; microtubule cytoskeleton organization and biogenesis; positive regulation of protein transport; membrane depolarization; peptidyl-serine phosphorylation; cellular response to insulin stimulus; long-term memory; establishment of cell polarity; actin cytoskeleton reorganization; insulin receptor signaling pathway; positive regulation of insulin receptor signaling pathway; phosphorylation; negative regulation of protein complex assembly; negative regulation of apoptosis