Thyroxine Binding Globulin (TBG) ELISA Kit for Mouse

Name: Mouse TBG ELISA Kit; Thyroxine Binding Globulin; MyBioSource
Brand: MyBioSource
SKU: MBS266493
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS266493

MBS266493 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thyroxine Binding Globulin (TBG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$350 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Thyroxine Binding Globulin (TBG), ELISA Kit

Full Product Name

Mouse Thyroxine Binding Globulin (TBG) ELISA Kit

Product Gene Name

TBG elisa kit

Species Reactivity

Mouse

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

46,325 Da

OMIM

314200

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TBG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TBG. It may not necessarily be applicable to this product.

NCBI GI #

205277441

NCBI GeneID

6906

NCBI Accession #

NP_000345.2

UniProt Secondary Accession #

D3DUX1

UniProt Related Accession #

P05543

GenBank Nucleotide #

NM_000354.5

NCBI Official Full Name

thyroxine-binding globulin

NCBI Official Synonym Full Names

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7

NCBI Official Symbol

SERPINA7

NCBI Official Synonym Symbols

TBG

UniProt Protein Name

Thyroxine-binding globulin

UniProt Synonym Protein Names

Serpin A7; T4-binding globulin

UniProt Gene Name

SERPINA7

UniProt Synonym Gene Names

TBG

UniProt Entry Name

THBG_HUMAN

NCBI Protein Information

thyroxine-binding globulin; serpin A7; T4-binding globulin; thyroxin-binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7

NCBI Summary for TBG

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.[provided by RefSeq, Jun 2012]

UniProt Comments for TBG

SERPINA7: Major thyroid hormone transport protein in serum. Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency). Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein- bound iodine but are euthyroid. Belongs to the serpin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: Xq22.2

Cellular Component: extracellular space; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; hormone binding

Biological Process: response to drug; response to peptide hormone stimulus; aging; response to corticosterone stimulus; post-embryonic development; response to vitamin A

Research Articles on TBG

1. TBG allosteric regulation is entropy driven. The presence of multiple S states may allow more efficient T4 release due to protease activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with TBG elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with TBG and Neoplasms
Carcinoma Antibodies	>1 publications with TBG and Carcinoma
Precancerous Conditions Antibodies	>1 publications with TBG and Precancerous Conditions
Inflammation Antibodies	>1 publications with TBG and Inflammation
Fatty Liver Antibodies	>1 publications with TBG and Fatty Liver

Organs/Tissues associated with TBG elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with TBG and Liver