ERG25 Antibody (C-Term) Blocking Peptide

Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

SC4MOL: Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: EC 1.14.13.72; Oxidoreductase; Membrane protein, multi-pass; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q32-q34

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; plasma membrane

Molecular Function: C-4 methylsterol oxidase activity

Biological Process: cholesterol biosynthetic process; fatty acid metabolic process; steroid metabolic process