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G Protein Beta Subunit Like Protein (GbL), Recombinant Protein

Recombinant G Protein Beta Subunit Like Protein (GbL)

(#MBS2009426)

Gene Names:

GbL; MLST8; LST8; POP3; WAT1; GbetaL

Other Names:

target of rapamycin complex subunit LST8 isoform a; MTOR associated protein; LST8 homolog (S. cerevisiae)

Host/Reactivities:

Host: E Coli

Purity:

> 95%

Applications:

Positive Control (PC) ; Immunogen ; SDS-PAGE ; Western Blot (WB).(May be suitable for use in other assays to be determined by the end user.)

Lenaldekar, Inhibitor

Lenaldekar

(#MBS5774151)

Other Names:

LDK

Purification:

98%

View Details

$Testing Data (Published customer image: Massive SIV infection of LN and intestinal macrophages in CD4-depleted RMs. (a) Immunofluorescence staining for T cell (CD3; blue) and macrophage (CD68 and/or CD163; green) lineage markers combined with in situ hybridization for SIV vRNA (red) in the LN isolated at day 42 post-infection from one representative undepleted control (left) and one CD4-depleted RM. The vast majority of SIV vRNA+ cells express CD3 in undepleted control but express CD68/CD163 in CD4-depleted RM. (b) The same staining is shown for colon (top) and jejunum (bottom) tissues in two representative CD4-depleted animals. (c) Quantitative image analysis of LN and mucosal tissues showing the fraction of SIV vRNA+ cells that express CD3 or CD68/CD163 in CD4-depleted (n = 12; the 8 animals in this study plus the 4 in Ortiz et al 2011) or undepleted control RMs (n = 6; two SIVmac251 infected animals belonging to a different study were added as controls). (d) Relative abundance of SIV vRNA+ in productively infected T cells and macrophages, determined by measuring the volumetric sum of the SIV vRNA+ intensity integration values in situ from confocal images collected under identical laser settings, is shown in four CD4-depleted RMs. Macrophages on average have higher per cell SIV vRNA+ content compared to CD4+ T cells within the same host. Statistical analyses were determined by Mann-Whitney test.From: Micci L, Alvarez X, Iriele RI, Ortiz AM, Ryan ES, et al. (2014) CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells. PLoS Pathog 10(10): e1004467.)$

CD163, Monoclonal Antibody

MOUSE ANTI HUMAN CD163

(#MBS212351)

Gene Names:

CD163; M130; MM130

Other Names:

scavenger receptor cysteine-rich type 1 protein M130 isoform a; CD163 molecule

Host/Reactivities:

Host: Mouse

Isotype/Clone:

Isotype: IgG1 / Clone EDHu-1

Applications:

Immunohistochemistry-Frozen (IHC-Fr),Immunohistochemistry-Paraffin (IHC-p), ELISA (EIA), Flow cytometry (FC), Immunofluorescence (IF), Immunoassay (IY), Western Blot (WB)

$Testing Data (Published customer image: Massive SIV infection of LN and intestinal macrophages in CD4-depleted RMs. (a) Immunofluorescence staining for T cell (CD3; blue) and macrophage (CD68 and/or CD163; green) lineage markers combined with in situ hybridization for SIV vRNA (red) in the LN isolated at day 42 post-infection from one representative undepleted control (left) and one CD4-depleted RM. The vast majority of SIV vRNA+ cells express CD3 in undepleted control but express CD68/CD163 in CD4-depleted RM. (b) The same staining is shown for colon (top) and jejunum (bottom) tissues in two representative CD4-depleted animals. (c) Quantitative image analysis of LN and mucosal tissues showing the fraction of SIV vRNA+ cells that express CD3 or CD68/CD163 in CD4-depleted (n = 12; the 8 animals in this study plus the 4 in Ortiz et al 2011) or undepleted control RMs (n = 6; two SIVmac251 infected animals belonging to a different study were added as controls). (d) Relative abundance of SIV vRNA+ in productively infected T cells and macrophages, determined by measuring the volumetric sum of the SIV vRNA+ intensity integration values in situ from confocal images collected under identical laser settings, is shown in four CD4-depleted RMs. Macrophages on average have higher per cell SIV vRNA+ content compared to CD4+ T cells within the same host. Statistical analyses were determined by Mann-Whitney test.From: Micci L, Alvarez X, Iriele RI, Ortiz AM, Ryan ES, et al. (2014) CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells. PLoS Pathog 10(10): e1004467.)$

CD163, Monoclonal Antibody

MOUSE ANTI HUMAN CD163

(#MBS215285)

Gene Names:

CD163; M130; MM130

Other Names:

scavenger receptor cysteine-rich type 1 protein M130 isoform a; CD163 molecule

Host/Reactivities:

Host: Mouse

Isotype/Clone:

Isotype: IgG1 / Clone EDHu-1

Applications:

Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoassay (IY), Immunohistology Paraffin, Western Blot (WB)

CD229, Monoclonal Antibody

MOUSE ANTI HUMAN CD229

(#MBS212512)

Gene Names:

CD229; LY9; hly9; mLY9; SLAMF3

Other Names:

T-lymphocyte surface antigen Ly-9 isoform b; lymphocyte antigen 9

Host/Reactivities:

Host: Mouse

Isotype/Clone:

Isotype: IgG1 / Clone HLy9.1.25

Applications:

Flow cytometry (FC/FACS), Immunoprecipitation (IP)

PP242, Inhibitor

PP242

(#MBS8506459)

Gene Names:

PP242

Purification:

>99%

HBXIP / Hepatitis B Virus X-Interacting Protein, Recombinant Protein

Human HBXIP / Hepatitis B Virus X-Interacting Protein Recombinant Protein

(#MBS2902402)

Gene Names:

HBXIP; LAMTOR5; XIP

Other Names:

Hepatitis B virus X-interacting protein; HBV X-interacting protein; HBX-interacting protein; ragulator complex protein LAMTOR5; late endosomal/lysosomal adaptor; MAPK and MTOR activator 5

Host/Reactivities:

Host: E Coli

Purity:

>95% by SDS-PAGE

Applications:

ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array

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MLST8, Polyclonal Antibody

Anti-MLST8 Antibody Picoband

(#MBS1758596)

Gene Names:

MLST8; GBL; LST8; POP3; WAT1; GbetaL

Other Names:

Zinc finger protein Helios; aryl hydrocarbon receptor nuclear translocator like 2; Cytoskeleton-associated protein 5; Colonic and hepatic tumor overexpressed gene protein; Ch-TOG; CKAP5; KIAA0097; Tar...

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse, Rat

Purification:

Immunogen affinity purified.

Isotype/Clone:

Isotype: Rabbit IgG

Applications:

ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)